The most effective treatments for preventing relapse in first episode psychosis: a new systematic review and meta-analysis

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Patients with first episode psychosis often relapse after initial remission, so it is perhaps surprising that treatment guidelines for the condition are generally based on poor quality evidence. Antipsychotic drugs are frequently discontinued, but clinicians don’t have ready access to information that shows how to determine which patients can be successfully tapered off of antipsychotic [read the full story…]

The Calgary Depression Scale for Schizophrenia is the best instrument for diagnosing depression in schizophrenia

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Depression can be difficult to detect and diagnose and this difficulty only increases when other mental health conditions are also present. This systematic review conducted by a team of researchers from Groningen in the Netherlands, set out to identify the best instrument for diagnosing depression in people with schizophrenia. Their concern was that some diagnostic [read the full story…]

Should we be prescribing antipsychotics to young people with bipolar disorder?

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This systematic literature review and meta-analysis conducted by researchers from the University of Nebraska Medical Center, will be of interest to all clinicians who treat paediatric bipolar disorder. Treatment decisions for young people have previously been based on extrapolation from adult trials, case reports, open label trials or expert opinion. This new study provides a [read the full story…]

Cognitive reframing may help reduce anxiety, depression and stress in carers of people with dementia

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Cognitive reframing is a technique used to reduce unrealistic or irrational thoughts and think in a more constructive way instead. It’s used as part of cognitive behavioural therapy. Carers of people with dementia sometimes respond inappropriately to the behaviour of the person with dementia. The stress and pressure of caring for their loved one may [read the full story…]

Oral health advice for people with serious mental illness

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The aim of this systematic review from the Cochrane Schizophrenia Group was to assess the effectiveness of oral health advice in reducing morbidity, mortality and preserving the quality of life in people with serious mental illness. A number of studies have found links between mental health problems and poor oral health and we have highlighted [read the full story…]

The evidence remains weak for the long-term effectiveness of counselling in primary care

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General practices in the UK sometimes offer counselling to people with mental health or psychosocial problems. This is an alternative to standard GP care or the conventional treatments such as cognitive behaviour therapy or antidepressants. However, recent guidelines have not been able to recommend the use of counselling because the evidence-base remains weak in comparison [read the full story…]

Review suggests evidence in favour of risperidone but warns of continued adverse events

Antipsychotic overprescribing is common in people with learning disabilities who have no record of severe mental illness.

This systematic review set out to look at the efficacy of atypical antipsychotic medication, also known as second generation antipsychotics, commonly used in the treatment of schizophrenia. There continues to be debate around whether these second-generation medications are safer or more effective than typical antipsychotics as they still can produce severe side effects. Other posts [read the full story…]

Psychiatrists need to carry out more physical health checks for metabolic complications, says systematic review

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A new systematic review conducted by a research team from Leicester suggests that psychiatrists are failing to carry out physical health checks for metabolic complications common in patients with mental illness, in particular those who are prescribed antipsychotics. Many hospitals now have guidelines in place to ensure that patients on antipsychotics are monitored to check [read the full story…]

Family-based prevention and multi-component interventions may help prevent alcohol misuse in young people, say new systematic reviews

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Readers interested in preventing alcohol misuse in young people will find these two new systematic reviews from the Cochrane Library worth looking at in more detail. Both reviews have been conducted by researchers from Brookes University in Oxford, who searched for randomised controlled trials including school aged children up to 18 years old. The first [read the full story…]

Little is known about public attitudes to people with learning disabilities from current research

There is sparse evidence for the efficacy and safety of antipsychotics in people with learning disabilities.

National policy relating to the support of people with learning disabilities has social inclusion as a key aim. The success of this aim is affected by the response of the general public. The author of this review set out to look at general population based research into awareness, attitudes and beliefs regarding learning disabilities from [read the full story…]