Quetiapine monotherapy helps people with generalised anxiety disorder, but side effects may limit its use

Future research needs to shed light on psilocybin-assisted treatment among people with treatment-resistant depression and experiences and side effects.

People with generalised anxiety disorder (GAD) often fail to achieve remission (recovering fully from their disease) despite standard treatments. This systematic review examines the efficacy and tolerability of second-generation antipsychotics (SGAs) for generalised anxiety disorder as either: augmentation therapy, i.e. using it alongside other treatments monotherapy, i.e. using it as a stand-alone treatment The reviewers [read the full story…]

Second generation antidepressants all equally effective in treating social anxiety disorder, according to new systematic review

Antidepressants for anxiety

With a lifetime prevalence of about 12% and a 12-month prevalence of around 4%, social anxiety disorder is the most prevalent anxiety disorder and one of the most common psychiatric conditions. This systematic review conducted by researchers from the Federal University of Rio de Janeiro in Brazil, aimed to assess the effectiveness of different second [read the full story…]

Depression significantly increases the risk of stroke: new systematic review

stroke

There is a considerable body of research that explores the links between depression and other diseases (e.g. cancer and cardiovascular disease). Many studies have also been published that investigate the relationship between depression and stroke, but the results are inconsistent. Researchers from Harvard have now conducted a systematic review and meta-analysis of prospective cohort studies [read the full story…]

Memantine may reduce fractures and cholinesterase inhibitors may increase syncope in dementia: new systematic review

shutterstock_79586893

Last week I blogged about a study that showed how some dementia drugs may help reduce the progression of the disease and delay admission to care homes for people with the condition. This new systematic review carried out by a research team from Harvard Medical School investigates the potential side effects of two dementia drugs: [read the full story…]

New meta-review of computerised cognitive behaviour therapy (cCBT) packages for depression

shutterstock_48995119 laptop happy man

Researchers from Nottingham University have published a meta-review that aims to evaluate the quality of existing reviews and to enable reliable comparisons of alternative computerised cognitive behaviour therapy (cCBT) packages for treating mild to moderate depression with or without anxiety. The reviewers conducted a systematic search and found 12 systematic reviews from 10 studies covering [read the full story…]

Drug and talking treatments for adults with ADHD: new systematic review and meta-analysis

shutterstock_60231907 adhd

Attention deficit hyperactivity disorder (ADHD) is a group of behavioural symptoms that include inattentiveness, hyperactivity and impulsiveness. ADHD is often thought of as a childhood problem, but it can be a lifelong condition, and many children continue to have symptoms as a teenager and adult. It is estimated that nearly two-thirds of children with ADHD [read the full story…]

Melatonin administration in autism spectrum disorder improved sleep parameters, daytime behaviour and had minimal side effects

Sleep

The researchers in this review looked at findings related to melatonin in autism spectrum disorders (ASD), including autistic disorder, Asperger syndrome, Rett syndrome, and pervasive developmental disorders, not otherwise specified. From a search of databases, they were able to find 35 studies that met review’s inclusion criteria. It was possible to perform a meta-analysis on [read the full story…]

Brief psychological therapies are effective for treating depression and anxiety in primary care

shutterstock_32557231

Psychological therapies given to people with depression, anxiety or mixed disorders in primary care are usually delivered over a shorter time period than in secondary care. In the UK, 6 sessions is a common treatment length, which contrasts to the 12-24 sessions that have been the subject of most trials of psychological therapies in secondary care [read the full story…]

Psychotherapies are effective treatments for depression and anxiety in low and middle income countries

African family - Anna Omelchenko Shutterstock

A new meta-analysis published in the African Journal of Psychiatry investigates the efficacy of psychological treatments for depression and anxiety disorders in low and middle income countries. To date there has perhaps existed a view that psychological mindedness is missing amongst the population of developing countries. There is good evidence that psychological treatments work as [read the full story…]

Tooth loss three times higher in people with serious mental illness

shutterstock_3909307 middle aged man with missing teeth

People with severe mental illnesses like schizophrenia or bipolar disorder are over three times more likely to lose their teeth because of poor oral health than the general population. The research, published in the September issue of the British Journal of Psychiatry, shows that psychiatric patients have not shared in recent improvements in dental health. [read the full story…]