Lithium is a medicine that has been used for over 50 years to treat depression and bipolar disorder. It comes in two forms that are used clinically: lithium carbonate and lithium citrate. A certain level of the drug is needed in the blood stream for it to be effective, but if the level rises too [read the full story…]
Following on from my post yesterday about screening tools for depression in later life, here is a new meta-analysis that explores the efficacy of antidepressants for the treatment of major depressive disorder (MDD) in patients aged ≥ 55 years. The researchers from the University of Modena and Reggio Emilia in Italy just searched PubMed for [read the full story…]
Healthcare providers are always on the look out for ways to improve the detection and diagnosis of depression in primary care. It’s a prevalent illness amongst Europeans with 6.9% of people suffering from it in any 12-month period. We know that 50-70% of depressed patients consult their GP during an episode, so improving systems for [read the full story…]
The demand for psychological therapies far outstrips the supply and in this ongoing period of austerity we surely need to produce some cost-effective alternatives. One method that patients can attempt pretty much on their own is self-help provided through books, CDs, DVDs and websites. This new systematic review claims to be the first to bring [read the full story…]
Seasonal affective disorder (winter depression) is a type of depression that recurs in the autumn and lasts until the spring. It is similar to regular depression except sufferers are usually very tired and have an increase in their appetite. It is more common in countries with few daylight hours in winter. People with seasonal affective [read the full story…]
A large number of systematic reviews and guidelines have been published in recent years to assist clinicians in prescribing the best antidepressants for treating depression. This new meta-analysis conducted by researchers from Austria and the US, sets out to compare the benefits and harms of second generation antidepressant drugs in the treatment of major depressive [read the full story…]
Suicide is rarely far from the headlines these days, but the last week has seen a number of high profile stories in the mainstream media. First there was the tragic death of the much loved footballer Gary Speed, which has been followed by a huge amount of press coverage. Then on Saturday The Sun newspaper [read the full story…]
Patients with first episode psychosis often relapse after initial remission, so it is perhaps surprising that treatment guidelines for the condition are generally based on poor quality evidence. Antipsychotic drugs are frequently discontinued, but clinicians don’t have ready access to information that shows how to determine which patients can be successfully tapered off of antipsychotic [read the full story…]
This systematic literature review and meta-analysis conducted by researchers from the University of Nebraska Medical Center, will be of interest to all clinicians who treat paediatric bipolar disorder. Treatment decisions for young people have previously been based on extrapolation from adult trials, case reports, open label trials or expert opinion. This new study provides a [read the full story…]
A new systematic review conducted by a research team from Leicester suggests that psychiatrists are failing to carry out physical health checks for metabolic complications common in patients with mental illness, in particular those who are prescribed antipsychotics. Many hospitals now have guidelines in place to ensure that patients on antipsychotics are monitored to check [read the full story…]
