Results: 2601

For: systematic review

Antibiotics for dental infections – Short or long duration courses?

Many drugs are licensed for use in Generalised Anxiety Disorder (GAD), but it is unclear what works best.

This review comparing short (3–5 days) or longer courses (≥7 days) of antibiotics for the treatment of dental infections in general practice only included one small RCTs. No differences were seen between short an dlong courses but the findings should be interpreted cautiously becaise of the limited data available.

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Body weight and perinatal depression: what’s the link?

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In her debut blog, Sarah Nicholson summarises a systematic review of pre-pregnancy BMI and the risk of antenatal and postnatal depression.

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Metronidazole for treatment of non-periodontal dental infections

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This review of whether metronidazole used as monotherapy or in addition to a β-lactam antibiotic offers any additional benefit over β-lactam monotherapy in non- periodontal dental infections includes 3 RCTs. The findings suggest that metronidazole does not provide superior clinical results compared to β-lactam antibiotics for the treatment of non-periodontal dental infections. However the evidence is limited and of low quality.

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Dental erosion in children and gastro-oesophageal reflux disease

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This review of the association between gastro-oesophageal reflux disease (GERD) and dental erosion in children included 13 observational studies. The findings suggest positive association association between GERD and dental erosion in children however this should be interpreted cautiously because of the wide variety of diagnostic methods used in the included studies.

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Periodontal treatment for preventing cardiovascular disease in people with periodontitis

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This Cochrane review update on the effects of periodontal therapy for primary or secondary prevention of CVD in people with chronic periodontitis includes 2 studies which provide very low certainty evidence. No additional studies have been included since the last update in 2019.

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Psychotherapeutic approaches and treatment efficacy for comorbid BPD and PTSD

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Natalie Kashirsky summarises a systematic review on optimising treatment for comorbid BPD (borderline personality disorder) and PTSD (post-traumatic stress disorder).

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Do therapist factors have an impact on PTSD outcomes in children and adolescents?

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In his debut blog, Sam Thompson explores a paper that looks into the associations between therapist factors and treatment efficacy in randomised controlled trials of trauma‐focused CBT for children and youth with PTSD.

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Burning mouth syndrome – topical interventions

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This review assessing the effectiveness of topical interventions in the management of burning mouth syndrome (BMS), based on the core outcome domains recommended by the Initiative on Methods, Measurement, and Pain Assessment in Clinical Trials (IMMPACT) includes 8 RCTs and higlights the need to apply standardised outcome measures in future studies.

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Mastication and chronic disease in older adults

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In this blog Carly Ross assess a review of the associations between objectively assessed masticatory performance, chronic systemic diseases and physical function in older adults.

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Early and delayed dental implant loading

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This review of the outcomes of early and delayed loading of dental implants included 18 RCTs. The findings suggest that early and delayed loading protocols had similar clinical outcomes. However none of the included studies was at a low risk and 13 of the 18 studies were considered to be at high risk of bias. While the findings are similar to other reviews teh availabel evidence is of low to very low certainty.

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