Results: 2607

For: systematic review

Depression and Diabetes: a two-way street?

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Depression is often found in people with chronic long-term conditions such as diabetes.  Sometimes this can be a consequence of how the disease affects their lifestyle, difficulties of managing complications and coping with the unrelenting nature of chronic disease. However, there is recent evidence to show that depression is a risk factor for diabetes, partly [read the full story…]

Second generation antidepressants all equally effective in treating social anxiety disorder, according to new systematic review

Antidepressants for anxiety

With a lifetime prevalence of about 12% and a 12-month prevalence of around 4%, social anxiety disorder is the most prevalent anxiety disorder and one of the most common psychiatric conditions. This systematic review conducted by researchers from the Federal University of Rio de Janeiro in Brazil, aimed to assess the effectiveness of different second [read the full story…]

The reasons for alcohol misuse in bipolar disorder: a systematic review

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Alcohol misuse is common in people with mental health problems and the rates of drinking are particularly high in bipolar disorder. Studies show that the lifetime prevalence of substance use disorders is at least 40% in bipolar I patients (ref Cerullo et al). Researchers from Newcastle University in the UK have conducted a systematic review [read the full story…]

Two systematic reviews find little evidence for drug treatments in children under 12 with autism spectrum disorders

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Around 1% of the population have autism. There are a number of treatments available for the condition, including learning and development techniques, as well as medical interventions. However, there is little consensus about which drug treatments are most effective. A team of researchers from Nashville have recently published two systematic reviews in the Pediatrics journal, [read the full story…]

Bacteraemia due to everyday oral activities

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The aim of this review was to investigate the robustness of the observations on the influence of oral hygiene, gingival and periodontal status on the development of bacteraemia from everyday oral activities (B-EOA), analysing its prevalence, duration, magnitude and bacterial diversity. The authors searched MEDLINE-PubMed, the Cochrane Library and Embase for studies on B-EOA. They [read the full story…]

Depression significantly increases the risk of stroke: new systematic review

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There is a considerable body of research that explores the links between depression and other diseases (e.g. cancer and cardiovascular disease). Many studies have also been published that investigate the relationship between depression and stroke, but the results are inconsistent. Researchers from Harvard have now conducted a systematic review and meta-analysis of prospective cohort studies [read the full story…]

Memantine may reduce fractures and cholinesterase inhibitors may increase syncope in dementia: new systematic review

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Last week I blogged about a study that showed how some dementia drugs may help reduce the progression of the disease and delay admission to care homes for people with the condition. This new systematic review carried out by a research team from Harvard Medical School investigates the potential side effects of two dementia drugs: [read the full story…]

Emerging evidence on psychodynamic psychotherapy for children and adolescents

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The evidence-base for psychodynamic psychotherapy is growing. A meta-analysis by Shedler published in early 2010 showed that the effect sizes for psychodynamic therapy can be as large as for other ’empirically supported treatments’. However, there are fewer high quality studies available that look at the effectiveness of these therapies for young people. This systematic review [read the full story…]

Updated systematic review on surgery for oral cancer

An operating theatre.

The existing Cochrane systematic review on surgical treatment of oral and oropharyngeal cancers has been updated, with important changes to the conclusions. The reviewers concluded that  there was weak evidence to suggest that dissection of clinically negative neck nodes at the time of removal of the primary tumour reduced cancer recurrence.  However, there was insufficient [read the full story…]

New meta-review of computerised cognitive behaviour therapy (cCBT) packages for depression

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Researchers from Nottingham University have published a meta-review that aims to evaluate the quality of existing reviews and to enable reliable comparisons of alternative computerised cognitive behaviour therapy (cCBT) packages for treating mild to moderate depression with or without anxiety. The reviewers conducted a systematic search and found 12 systematic reviews from 10 studies covering [read the full story…]