Results: 2605

For: systematic review

Lithium is less expensive than olanzapine in treatment-resistant depression, but has unclear clinical benefits

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Treatment-resistant depression (TRD) still represents a challenge to psychiatric practice. Since patients have usually failed at least two antidepressants, drugs originally prescribed for other conditions are often tried as an augmentation (Souery er al., 2006). Amongst them, lithium (a mood-stabiliser used in the treatment of bipolar disorders) as well as atypical antipsychotics (AAPs, indicated for [read the full story…]

Currently no evidence to support repairing or replacing resin composite fillings for adults

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Over the past 30 years there has been an increase in the use of tooth-coloured composite resin filing materials as an alternative to amalgam for restoring posterior teeth.  Recent technical and material developments have improved the limitations of the early materials which were more likely to fail because of shrinkage, loss of form poor wear [read the full story…]

Currently no evidence to support repairing or replacing amalgam fillings for adults

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Dental amalgam has been the dental material of choice for many decades. Although, in recent years a greater focus on aesthetics and concerns related to the potential environmental impact of mercury coupled with a more conservative approach to cavity preparation and improvements in aesthetic restorative materials is leading to a decline it its use.  In [read the full story…]

Limited evidence suggests no difference in soft tissues aesthetics between immediate and conventional implant placement

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The aesthetic appearance of the soft tissues following dental implant placement is an important consideration  and potential more of an issue with immediate placement. The aim of this review was to compare the aesthetic  (soft tissue) outcomes of immediate (type 1) verses conventional (type 3) implant placement. Searches were conducted in PubMed, Embase, and the [read the full story…]

Systematic review identifies key parenting factors associated with adolescent depression and anxiety

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Parenting is a tough gig. As a mum of three, I can honestly say that nothing in my everyday professional life comes close to the trials and tribulations of guiding small people through toddlerhood and beyond. Parenting advice comes thick and fast from all corners, most of it unsolicited, some of it anecdotal, much of [read the full story…]

Cochrane review finds that haloperidol is an effective antipsychotic, but its side effects can be problematic

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Schizophrenia is a serious disorder characterised by delusions (including paranoid beliefs and hallucinations) and other symptoms such as blunted affect and reduced motivation. While relatively uncommon (lifetime prevalence is less than 1%), it is associated with serious social impairment (e.g., unemployment, homelessness), which in turn can result in physical health problems. As a result, the [read the full story…]

Cochrane review finds no evidence to support the use of user held records for patients with severe mental illness

The reviewers can't have been too pleased with the paucity of research in this field

The use of care plans and Wellness Recovery Action Plans (WRAP®) (Cook et al, 2009) within mental health is commonplace. In Wales, care planning is covered by legislation in the form of the Mental Health Measure (Welsh Government website, 2013). The care plans are designed to be developed and agreed in a collaborative way with input [read the full story…]

“Everyone’s a winner, all must have prizes!” but which psychotherapy for depression wins, if any?

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Previous meta-analyses in the field of depressive disorders have yielded mixed conclusions about which the most efficacious treatment is.  Within the process of any therapy, there are universal features such as; the therapeutic relationship, rationale for treatment, a patient and therapist belief in treatment, a confidential and respectful space for the patient and so on.  [read the full story…]

Meta-analysis finds that pituitary volume is not affected in people with first episode psychosis or schizophrenia

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* Declaration; I have published articles with two of the authors of this article, including on this topic, and know most of them professionally One influential model of the onset of psychotic disorders such as schizophrenia is the stress-vulnerability model, first put forward by Zubin and Spring in 1977. This model proposes that people at [read the full story…]

Reality orientation and skills training may improve cognition in dementia, but don’t jump to conclusions

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Well this is an interesting one. The abstract of a recent review by Carrion et al concludes that cognitive psychosocial interventions such as reality orientation and skills training improve cognition (Carrion, 2013). Woohoo, I thought; fantastic!  And then I read the review… Methods The authors searched the usual bibliographic databases for randomised and non-randomised controlled trials, [read the full story…]