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Bisphosphonate osteonecrosis (BON)

Derek Richards

The American Dental Association Center for Evidence-Based Dentistry has  just completed a critical review of a  paper by Migliorati et al published in 2012 which aimed to examine the prevalence of bisphosphonate osteonecrosis (BON) in the cancer population, prevention and treatment protocols, and quality of life issues.

This is a growing area of interest but, as the review notes the existing research at this time is limited  so dentists need to remain vigilant for BON and help to avert it.  Helpful guidance  is available from the  bisphosphonate page of the SDCEP  (Scottish Dental Clinical Effectiveness Programme) website .

Go to the ADA summary

Migliorati CA, Woo SB, Hewson I, Barasch A, Elting LS, Spijkervet FK, Brennan  MT; Bisphosphonate Osteonecrosis Section, Oral Care Study Group, Multinational Association of Supportive Care in Cancer (MASCC)/International Society of Oral Oncology (ISOO). A systematic review of bisphosphonate osteonecrosis (BON) in cancer. Support Care Cancer. 2010 Aug;18(8):1099-106. Epub 2010 Apr 22. Review. PubMed PMID: 20411279.

 

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Written by

Derek Richards is a specialist in dental public health, Director of the Centre for Evidence-Based Dentistry and Specialist Advisor to the Scottish Dental Clinical Effectiveness Programme (SDCEP) Development Team. A former editor of the Evidence-Based Dentistry Journal and chief blogger for the Dental Elf website until December 2023. Derek has been involved with a wide range of evidence-based initiatives both nationally and internationally since 1994. Derek retired from the NHS in 2019 remaining as a part-time senior lecturer at Dundee Dental School until the end of 2023.

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