Bisphosphonate osteonecrosis (BON)

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The American Dental Association Center for Evidence-Based Dentistry has  just completed a critical review of a  paper by Migliorati et al published in 2012 which aimed to examine the prevalence of bisphosphonate osteonecrosis (BON) in the cancer population, prevention and treatment protocols, and quality of life issues.

This is a growing area of interest but, as the review notes the existing research at this time is limited  so dentists need to remain vigilant for BON and help to avert it.  Helpful guidance  is available from the  bisphosphonate page of the SDCEP  (Scottish Dental Clinical Effectiveness Programme) website .

Go to the ADA summary

Migliorati CA, Woo SB, Hewson I, Barasch A, Elting LS, Spijkervet FK, Brennan  MT; Bisphosphonate Osteonecrosis Section, Oral Care Study Group, Multinational Association of Supportive Care in Cancer (MASCC)/International Society of Oral Oncology (ISOO). A systematic review of bisphosphonate osteonecrosis (BON) in cancer. Support Care Cancer. 2010 Aug;18(8):1099-106. Epub 2010 Apr 22. Review. PubMed PMID: 20411279.


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Derek Richards

Derek Richards is the Director of the Centre for Evidence-based Dentistry, Editor of the Evidence-based Dentistry Journal, Consultant in Dental Public Health with Forth Valley Health Board and Honorary Senior Lecturer at Dundee & Glasgow Dental Schools. He helped to establish both the Centre for Evidence-based Dentistry and the Evidence-based Dentistry Journal. He has been involved with teaching EBD and a wide range of evidence-based initiatives both nationally and internationally since 1994.

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