The American Dental Association Center for Evidence-Based Dentistry has just completed a critical review of a paper by Migliorati et al published in 2012 which aimed to examine the prevalence of bisphosphonate osteonecrosis (BON) in the cancer population, prevention and treatment protocols, and quality of life issues.
This is a growing area of interest but, as the review notes the existing research at this time is limited so dentists need to remain vigilant for BON and help to avert it. Helpful guidance is available from the bisphosphonate page of the SDCEP (Scottish Dental Clinical Effectiveness Programme) website .
Migliorati CA, Woo SB, Hewson I, Barasch A, Elting LS, Spijkervet FK, Brennan MT; Bisphosphonate Osteonecrosis Section, Oral Care Study Group, Multinational Association of Supportive Care in Cancer (MASCC)/International Society of Oral Oncology (ISOO). A systematic review of bisphosphonate osteonecrosis (BON) in cancer. Support Care Cancer. 2010 Aug;18(8):1099-106. Epub 2010 Apr 22. Review. PubMed PMID: 20411279.