As part of its excellent ‘Too Much Medicine’ series, the British Medical Journal last week published an important analysis of the current direction of travel in the field of dementia care. The article is hard to ignore, written as it is by highly authoritative academics from the UK and Australia, including Professor Carol Brayne, an [read the full story…]
When two interventions are demonstrably equivalent in terms of clinical outcomes, it is unclear which should be provided. One obvious decision rule in this case is to implement the intervention that is least costly and therefore most cost-effective. A recent economic evaluation by Patel and colleagues estimates the cost-effectiveness of adherence therapy for people with [read the full story…]
Get ready to amend your dopamine hypothesis and stop trying to wrap your neurons around the role of glutamate in the brain. The rising star of the neurobiological schizophrenia literature is…. Vitamin D. Yes, really. The more sceptical amongst you (including me) may feel that finding a vitamin deficiency in psychosis patients is perhaps not [read the full story…]
Some mental health interventions feel intuitively right. Exercise for depression is a great example. Of course, people suffering from low mood, poor motivation, lethargy and all of the other symptoms of depression will benefit from a jog around the park and some fresh air, right? The logical explanation for how this might help is fairly [read the full story…]
Around the world, certain places have gained notoriety as suicide hotspots. These places are often heights, such as bridges or cliffs, from which suicide by jumping is common. Although not a major contributor to overall suicide rates, suicides by jumping are of particular concern due to their ability to cause distress or physical harm to [read the full story…]
Suicidal thoughts and actions are typically discussed in relation to depression, but a number of studies have suggested suicide may also be linked to anxiety disorders. Anxiety disorders often co-occur with depression, and this may be masking a risk of suicide specifically related to anxiety. Today is World Suicide Prevention Day so it seemed relevant [read the full story…]
We often hear about postnatal depression, a well-recognised depressive episode in mothers occurring after the birth of their baby. However, 54.2% of women suffering from postnatal depression actually developed their depressive symptoms before or during pregnancy (Burt and Quezada, 2009). Around 10% of pregnant mothers have depression and this number increases each trimester. Women are less likely [read the full story…]
The harmful impact of depression extends far beyond the individual sufferer to caregivers, friends and family members. Children of people with depression are more likely to suffer from depression themselves. This may be due to both inherited and environmental factors. This new randomised controlled trial (RCT), published earlier this week in JAMA Psychiatry, set out [read the full story…]
There is a back to school feeling in the air in the Woodland this week, and so this comes to you with the help of my shiny new yellow pencil case. Epilepsy affects around 70 million people around the world and premature mortality is substantial with almost half of epilepsy-related deaths occuring in those younger [read the full story…]
Roughly 33% of stroke sufferers also develop depression at some point. This may be an under-estimate of the problem, as depression is difficult to detect in people with poor physical health. If missed, depression can led to reduced quality of life, increased disability and a worsening of physical symptoms. There are a whole host of [read the full story…]
