Samei Huda presents the findings of a new meta-analysis, which explores the prognostic significance of competing ways of defining and measuring brief psychotic episodes.
[read the full story...]Prognosis of brief psychotic episodes
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For: diagnostic test
Is it bipolar disorder or borderline personality disorder?
Murtada Alsaif considers the challenges facing psychiatrists in diagnosing bipolar disorder or borderline personality disorder. He reports on a recent qualitative study that explores the practical experience of psychiatrists and nurses and concludes that clinical diagnostic practice cannot reliably distinguish the two conditions.
[read the full story...]Can a machine learning approach help us predict what specific treatments work best for individuals with depression?
Marcus Munafo explores a recent study that uses a machine learning approach across two trials (STARD*D and CO-MED) to try and predict treatment outcomes (primarily focusing on the antidepressant citalopram) for depression.
[read the full story...]Vertical root fracture diagnosis with CBCT – insufficient evidence
Only 4 small studies at high risk of bias were available for this review of cone-beam computed tomography (CBCT) for diagnosis of vertical root fracture, providing insufficient evidence to suggest that CBCT is a reliable test.
[read the full story...]Cognitive tests for dementia: MMSE, Mini-Cog and ACE-R
Akshay Nair explores the results of a systematic review of cognitive tests for dementia and mild cognitive impairment, which focuses on the MMSE, Mini-Cog, ACE-R and MoCA instruments. Along the way he explains how diagnostic tests work and how sensitivity and specificity are useful measures to get your head around.
[read the full story...]Rise of the machine learning algorithm: the future of diagnosing schizophrenia?
Samei Huda reviews a meta-analysis of multivariate pattern recognition studies, which aims to detect neuroimaging biomarkers for schizophrenia.
[read the full story...]Improving diagnosis of bipolar disorder: can blood-based diagnostic panels help?
Can blood-based diagnostic panels help us reduce the misdiagnosis and inappropriate treatment often experienced by people with bipolar disorder? Murtada Alsaif reviews a recent retrospective study that has some encouraging findings for biologically identifying the disease.
[read the full story...]Oral Cancer – DNA-image cytometry may have promise for early detection
This diagnostic review compared two computer aided adjunctive tests for oral cancer. Oral CDX and DNA-image cytometry. The results suggest that DNA-image cytometry has a highly significant potential over OralCDx brush biopsy as an accurate and simple diagnostic tool for clinically suspected oral precancer and oral cancer.
[read the full story...]Can early improvement be used to predict later response to antipsychotics in schizophrenia?
Tracey Roberts summarises a recent diagnostic test review, which suggests that early improvement can act as a predictor of later response to antipsychotics in schizophrenia.
[read the full story...]Root fracture detection with CBCT
This review included 12 small in vitro and in vivo studies of Cone Beam Computed Tomography (CBCT) for the diagnosis of a root fracture. While the data suggest the ability to detect root fractures in non-endodontically treated teeth, the findings should be interpreted with caution.
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