This review of micro-invasive treatments for proximal caries included 13 split-mouth RCTs. There was moderate quality evidence to support sealing in infiltration of early proximal caries compared with non-invasive treatments such as diet and bio-film management and topical fluorides.
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This Cochrane review of antifibrinolytic agents for preventing bleeding in people on oral anticoagulants undergoing dental extractions or minor oral surgery included 4 RCTs. Topical tranexamic acid was effective in reducing post-operative bleeding following dental procedures.
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4 different vital pulp treatments for deep caries management of mature permanent molars were tested in this stud .The findings suggest that these techniques could be used but other approaches are available.
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9 studies were included in this review of the effect of splinted or unsplinted overdenture attachment system on clinical outcomes. The findings suggest no difference however, the quality of the evidence is limited.
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This review of metformin as an adjunct to scaling and root planing for chronic periodontitis included 5 RCTs that were of limited quality and mainly from one research group. The findings suggest benefit.
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This review of the effectiveness of Caries Risk Assessment (CRA) models included 32 studies providing limited evidence that CRA is effective for caries assessment and prediction.
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14 RCTs were included in this review of the effect of different reminders on oral hygiene and compliance in orthodontic patients. For most outcomes measured beneficial effects were seen in the patients receiving reminders.
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This review of the incidence and increment of root caries included 20 longitudinal studies that provided an overall estimate of incidence of 18.25% 1(95%CI; 13.22%-23–28%) and increment of 0.45 (95%CI; 0.37–0.53).
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Only one small study comparing compared pedicled buccal fat pad and buccal flap for the management of oro-antral communications and fistulae was found for this Cochrane review update of this clinical question.
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This review of the malignant transformation rate (TR) of oral lichen planus included 21 observational studies the majority of which were retrospective. The overall estimate of TR was 1.4%.
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