This review of the rate of malignant transformation of oral leukoplakia included 34 many retrospective observational studies. The estimated mean malignant transformation rate was 9.7% (95%CI; 7.8% to 11.7%).
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This review of the the efficacy of probiotics on oral Candida spp. includes 12 RCTs and suggests a possible benefit. However the quality of the evidence is limited so the findings should be intepreted cautiously.
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This review of the malignant transformation rate of oral lichen planus and associated risk factors included 33 studies. Using a strict definition the authors found a malignant transformation rate of 0.44%.
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This Cochrane review of the efficacy and safety of corticosteroids for the treatment of people with oral lichen planus(OLP) included 35 RCTs suggesting that they may be more effective than placebo for reducing the pain of symptomatic OLP but the reliability of the finding is low.
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This review ofwhether local computerised anaesthesia decreases the pain and disruptive behaviour in children when compared to conventional anaesthesia included 20 RCTs and suggested no diference between the two approaches.
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5 systematic reviews were included in this umbrella review of whether articaine or lidocaine is the most appropriate local anaesthetic solution for teeth with irreversible pulpitis undergoing root canal treatment.
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This new guideline from the American Dental Association is about the the appropriate use of systemic antibiotics for the urgent management of symptomatic irreversible pulpitis with or without symptomatic apical pulpitis, pulp necrosis and symptomatic apical periodontitis and pulp necrosis and localized acute apical abscess.
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This review of a possible association between vitamin D deficiency and recurrent aphthous stomatitis (RAS) included 5 case control studies providing limited evidence that low levels of serum vitamin D might be a risk factor for RAS.
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This review of the association between toombak use and oral leukoplakia and oral squamous cell carcinoma included 8 observational studies suggesting a strong association.
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This review of of the effects of oral supplementation on the prevention and/or treatment of oral mucositis in patients with cancer undergoing chemotherapy and/or radiotherapy included 12 RCTs and suggest that Zinc supplements may be beneficial.
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