Results: 1711

For: Treatment

Evidence-based youth psychotherapies: better than usual care, but only for less severe cases

Young people experiencing distress often fall through the cracks of a system built around diagnosis. Is treating the struggle, not the label, the answer?

Young people presenting with psychopathology may receive a wide range of treatments, such as family or cognitive behavioural therapy, skills training or behavioural contracting. Clearly it is important to know which of these interventions are best supported by evidence that they are effective in treating the presenting problem. Since some treatments have a significant evidence [read the full story…]

Some evidence that prophylactic antibiotics reduce implant failures

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Dental implants are being used increasingly and some implant failures may be due to bacterial contamination at insertion.  Prophylactic antibiotic regimens have been proposed to minimise infection. The aim of this review was to address the question, does the use of antibiotics, when compared with a control group, reduce the frequency of implant failure and [read the full story…]

Barriers to parenting programmes for children with behavioural problems: recommendations from parents and professionals

A child not listening

Disruptive behaviour problems (DPB) such as conduct problems or being oppositional and defiant affect a large proportion of young children. Many of these early behavioural problems predict negative outcomes such as underachieving at schools, future unemployment and criminal behaviour. Treatment of DPBs often begins during the school years once the condition is well-established, and when [read the full story…]

Systematic review shows higher quality RCTs needed on psychological effects of exercise for type 2 diabetes

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In the UK alone it’s estimated over two million adults have type 2 diabetes. That clearly warrants some serious research into its prevention and treatment, including the valuable role of exercise.  We also know the effects of diabetes are not confined to physical problems, linked as it is to reduced quality of life as well [read the full story…]

Observational study: antidepressant suicidality warnings may be counterproductive

Warning about pills

Selective serotonin reuptake inhibitors (SSRIs) have long been suspected to – paradoxically- increase suicidal behaviour in adolescent and pediatric patients. Consequently, national watchdogs started issuing black label warnings for all SSRIs to educate physicians and patients about associated risks. While clearly curbing the amount of antidepressant prescriptions, concerns have been voiced that this step has [read the full story…]

Transcranial magnetic stimulation (rTMS) enhances response to antidepressants: a rather flawed meta-analysis

An image of a brain

It’s a well-known fact that elves are allergic to unhappiness, so the fact that there are at least 350 million sufferers of depression worldwide1 is quite a problem. That’s before we’ve even mentioned the crippling mortality, morbidity and economic impact that depression causes. The trouble is, our treatments for depression aren’t perfect. Less than a [read the full story…]

Weight loss programmes commissioned from commercial providers offer more cost effective results according to recent trial

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This study explores the cost effectiveness of two weight loss programmes evaluated as part of a randomised controlled trial: (1) referral to a commercial provider (2) weight loss advice delivered through primary care channels, via GP or nurse.  Participants (who were over 18 years old and had a BMI of 27-35 with at least one [read the full story…]

Cost effectiveness analysis finds stepped care to be cheaper and more effective than CBT for bulimia nervosa

Bulimia concept - apple in mirror

Bulimia nervosa (BN) is an eating disorder; the diagnosis of which requires: persistent preoccupation with eating and an irresistible craving for food, episodes of overeating in which large amounts of food are consumed over a short period of time and potentially attempts to counteract the “fattening” effects of food by self-induced vomiting or laxative abuse. [read the full story…]

Updated review confirms substantial reductions in caries from fluoride varnish applications

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Varnishes have been is use as a delivery system for topical fluoride since the 1960s. Their effectiveness was highlighted to a greater extent following the publication of the first version of this Cochrane review in 2002. Since then use of fluoride varnish has been recommended in evidence-based guidance from SIGN, the SDCEP and the American [read the full story…]

Treatment of depression after a heart attack does not improve the long-term risk of adverse cardiac events but may increase survival

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Although there have been huge advances in the treatment of heart disease, it is still the UK’s biggest killer (more information on heart disease can be found at the British Heart Foundation’s website). Depression after a heart attack is common (roughly 20% prevalence) and can worsen heart disease and increase the risk of death.  A [read the full story…]