Oral leukoplakia – malignant transformation rate

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This review of the rate of malignant transformation (MT) of oral leukoplakia and potential risk factors included 26 mainly retrospective studies. The findings indicate a MT of 7.2% (95%CI; 5.40 to 9.10%) similar to those of another recent review whihc estimated MT as 9.8% (95%CI; 7.9 to 11.7%).

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Is trauma a transdiagnostic risk for mental health problems? Recent umbrella meta-analysis suggests yes

Mental health services worldwide operate using discrete categories, but significant symptom overlap between different mental health disorders suggests that transdiagnostic approaches may be plausible.

In her debut blog, Megan Bailey summarises an umbrella review of systematic reviews and meta-analyses on whether psychological trauma can be considered as a transdiagnostic risk factor for mental health disorders.

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What impact has the Russian invasion had on youth mental health in Ukraine?

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In his debut blog, Tyler Elliot considers a case-control study focusing on the impact of the Russian invasion on the mental health of adolescents in Ukraine that suggest the risk for developing mental health conditions has likely been exacerbated in war-affected areas.

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Blood-based inflammatory markers in acute vs chronic schizophrenia

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Éimear Foley summarises a recent meta-analysis, which looks at alteration patterns of peripheral concentrations of cytokines and associated inflammatory proteins in acute and chronic stages of schizophrenia.

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Addressing premature mortality in mental illness: the “Gone Too Soon” framework

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Alvin Richards-Belle and Humma Andleeb review the Gone Too Soon framework, published yesterday in The Lancet Psychiatry, which suggests priorities for action to prevent premature mortality associated with mental illness and mental distress.

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Online experiences: a risk factor for suicide?

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Louise La Sala and Jo Robinson review a UK-wide case series study of young people who died by suicide, which explores their previous suicide-related online experiences.

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Multiracial young adults at higher risk of mental illness compared to their monoracial counterparts, according to US university research

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Andie Ashdown summarises a cross-sectional study exploring mental health disparities between multiracial and monoracial young people in the United States.

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Suicide and self-harm in nurses and midwives: urgent attention needed according to new systematic review

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Ben Hannigan summarises a recent systematic review exploring the prevalence, risk factors and interventions for suicide and self-harm in nurses and midwives.

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Stressed mums and depressed young ones: does parenting play a moderating role?

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In her debut blog, Svenja Geissler reviews a Norwegian cohort study, which suggests that different parenting styles can strengthen or weaken the link between prenatal stress in mothers and depression or anxiety in their offspring.

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Does a diagnosis of severe physical illness elevate suicide risk?

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Dona Matthews reviews a retrospective cohort study of 47 million people exploring the risk of suicide after diagnosis of severe physical illness, such as low-survival cancers, chronic ischaemic heart disease, chronic obstructive pulmonary disease, and degenerative neurological conditions such as Huntington’s disease.

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