5 good but small RCTs were identified for this review of topical tranexamic acid (TXA) for minor oral surgery in patients on anticoagulants. The findings suggest that TXA irrigation and mouthwash may reduce the risk of bleeding.
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This review of mouthwashes for the management of dentine hypersensitivity included 7 small studies all at high risk of bias. While minor benefits in patients’ subjective perception were seen the limited quality of the study means these findings should be interpreted with caution.
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63 RCTs contributed to this network meta-analysis of the effectiveness of anti-plaque agents. Results suggested that toothpastes containing triclosan-copolymer or chlorhexidine and mouthrinses containing essential oils or chlorhexidine had the most effect on plaque indicies at 6 months.
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This review of essential oils mouthwashes included 16 RCTs and found them to be more effective for the reduction of plaque and gingival inflammation than mechanical plaque control either alone (placebo) or in combination with mouthwashes with CPC.
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This study from the INHANCE collaboration pooled data from 12 case-controlled studies. Long-term use (35 yrs) of mouthwash was associated with an increase risk OR=1.15 (95%CI; 1.01 to 1.30) of head and neck cancer but with regular (>2 x daily), long-term (>35 years) use OR = 1.75 (95%CI; 1.25 to 2.48).
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This review of the effectiveness of neem-based mouthwash for improving plaque control and gingival health only identified 3 low quality RCTs of short duration providing little evidence to assess its effectiveness.
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This review identified 12 trials of mouthwashes and toothpastes for oral malodour. Those products with active ingredients reduced oral malodour but the overall quality of the available evidence was weak.
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This new review covers the board topic of the efficacy of anti-plaque chemical formulations for managing gingivitis. 87 heterogeneous studies found a statistically significant benefit with most test products.
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This review of mouthwash use in patients having fixed banded orthodontic treatment included 15 small studies and suggests that they reduce plaque levels. However the clinical relevance of the findings are uncertain and larger well conducted studies are needed.
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The role of chlorhexidine (CHX) in inhibiting plaque growth has been extensively studied. The aim of the review was to evaluate the effectiveness of CHX-containing dentifrice (DF) or gel (CHX DF/gel) compared with CHX mouthwash (MW). Searches were conducted in Medline-PubMed, the Cochrane Central Register of Controlled Trials (CENTRAL) and Embase databases. Randomized controlled trials [read the full story…]
