What’s the ‘optimal dose’ of psychotherapy to improve social functioning in people with depression?

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The majority of studies about depression measure outcomes using a scale such as the Hamilton Depression Rating Scale (PDF), which is a questionnaire that patients complete with a health professional. This new randomised controlled trial by researchers from the Arkin Institute for Mental Health in Amsterdam uses the Hamilton Depression Scale, but is also measures social [read the full story…]

More evidence to support the association between depression and an increased risk of stroke

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I’ve blogged before about the association between stroke and depression. It seems logical that people who have strokes are at risk of depression afterwards, but studies have also shown a more concrete relationship between the two conditions. This new meta-analysis conducted by a research team from Soochow University in China looks at prospective studies to [read the full story…]

Depression in adults with a chronic physical health problem: new update from NHS Evidence

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NICE published a clinical guideline on the treatment and management of depression in adults with chronic physical health problems in 2009. This new evidence update refreshes that guidance by searching for new systematic reviews and randomised controlled trials on the subject and summarising them in a short (16 page) document. The authors searched a range [read the full story…]

SIGN publish new patient booklet for women who have depression or psychosis during pregnancy or after the birth of their baby

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SIGN (Scottish Intercollegiate Guidelines Network) are the main producer of clinical practice guidelines in Scotland. They have produced a wide range of guidelines relevant to mental health over the years including publications on perinatal mood disorders and the non-pharmaceutical management of depression. They have also been widely praised for their excellent mobile apps, the first [read the full story…]

Non-directive supportive therapy is effective for adult depression, according to new meta-analysis

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We know that various psychotherapies are effective in treating adult depression, but there remains quite a bit of uncertainty about which specific therapies work best and what factors within the treatments contribute most to the improvement. This new meta analysis from a mixed group of researchers from the Netherlands, USA, Switzerland and Sweden, looks at [read the full story…]

Insufficient evidence to recommend first line treatment for depression in cancer patients

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Depression is at least three times as common in patients with cancer compared to the rest of the population. Studies show that major depression occurs in 16% of cancer patients, with combined minor depression and dysthymia reported in 22% of people with cancer. Depression also appears to be more prevalent amongst people with certain cancers (pancreatic, [read the full story…]

Rethinking physical activity for depression: what’s cost effective?

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Exercise is a good thing right? It seems obvious that people who are affected by mental health problems would benefit from getting themselves outside and becoming more active, but are these ‘treatments’ value for money when they are delivered in a structured way? The current NICE depression guideline recommends ‘structured’ physical activity programmes for depression [read the full story…]

Can pregnant women with depression take SSRI antidepressants without harming their unborn baby?

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People who take psychiatric drugs are well aware of the daily trade-off between the benefits and the harms of their medication. This is a key consideration for pregnant women with depression, who don’t just have to consider the side effects that may strike them, but also the impact they may have on their unborn child. [read the full story…]

Group CBT is an effective treatment for depression, but the evidence remains quite weak

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The NICE depression guidance recommends a stepped-care model for treating mild to moderate depression (see figure 11 below). A considerable amount of funding has gone towards the Improving Access to Psychological Therapies initiative in England, but despite this the availability of individual therapy remains limited and relatively few people with depression receive the kind of [read the full story…]

Insomnia can help predict depression

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People with depression frequently have trouble sleeping and this restlessness often first appears at the onset of the depressive disorder and continues until well after the depression has been successfully treated. This new meta-analysis conducted by a research team from the University of Freiburg Medical Center in Germany, investigates if insomnia can be viewed as [read the full story…]