Spotting the storm before it breaks: mapping the prodrome of severe mental illness

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People with severe mental illness often face years of poor health before diagnosis. A new study uses machine learning and clinical notes to map the early warning networks of symptoms that could help us intervene earlier.

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Cannabis, psychosis and the structural realities for ethnic minorities

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KCL MSc student Geetika Sharma reviews a study that looks at the contribution of cannabis use to the increased psychosis risk among minority ethnic groups in Europe.

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Cannabis legalisation: what can we learn about psychosis risk from the great Canadian (quasi) experiment?

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What happens to psychosis risk when cannabis becomes easier to access? According to this Canadian study, the risk goes up. Shuichi Suetani explores what we can learn from one of the countries leading the way in drug policy reform.

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Schizophrenia and cannabis use: new evidence measures risk of relapse

Over 20% of cannabis users experience a psychotic relapse within 24 months of treatment.

In her debut blog, Sally Turner considers a recent study on cannabis use and clinical outcomes in people with first-episode schizophrenia spectrum disorders over 24 months of treatment.

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Can contingency management help people with psychosis give up cannabis? The CIRCLE trial

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Ian Hamilton summarises the recently published CIRCLE trial, which looks at the clinical and cost-effectiveness of contingency management for cannabis use in early psychosis.

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Daily skunk cannabis use associated with a 5-fold increase in psychosis risk

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Luke Sheridan-Reins explores a recent paper on the contribution of cannabis use to variation in the incidence of psychotic disorder across Europe.

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What can genetics tell us about the link between cannabis and schizophrenia? #MHQT

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Suzi Gage summarises a recent GWAS of lifetime cannabis use, which reveals new risk loci, genetic overlap with psychiatric traits, and a causal influence of schizophrenia. Interesting new evidence ahead of our Mental Health Question Time #MHQT event in London tomorrow.

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Is Cannabidiol (CBD) an effective antipsychotic?

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Luke Sheridan Rains publishes his debut blog on a recent multicentre RCT of Cannabidiol (CBD) as an adjunctive therapy for people with schizophrenia, which suggests that CBD had a beneficial, but modest impact on positive psychotic symptoms and severity of illness when used alongside existing antipsychotics.

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Joint risks? Tobacco and cannabis and psychotic symptoms

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James MacCabe appraises a recent study, which looks at the association of combined patterns of tobacco and cannabis use in adolescents who go on to experience psychotic symptoms.

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