Orthognathic surgery: antibiotic prophylaxis reduced surgical site infection

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This new Cochrane review identified 11 RCTs and suggests that for those undergoing orthognathic surgery, long term antibiotic prophylaxis decreased the risk of surgical site infection compared with short-term regimens.

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Dental implant failures reduced with prophylactic antibiotic suggests review

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This new review covers similar ground to the 2013 Cochrane review. It includes non-randomised controlled trials, but as with the Cochrane review the findings suggest that antibiotics reduce early implant failure.

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Antibiotic prophylaxis in surgery – SIGN Guideline 104

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The Scottish Intercollegiate Guidelines Network  (SIGN) has just launched their updated guideline on antibiotic prophylaxis in surgery.  SIGN’s first guideline of this topic (SIGN 45)  was published in 2000 and updated in 2008.  The guideline does not aim to provide every surgical speciality with a comprehensive text on preventing  surgical site infection (SSI), but rather [read the full story…]

No evidence on whether antibiotic prophylaxis is effective or ineffective against bacterial endocarditis in people at risk who need invasive dental procedures

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Bacteraemia is common following dental procedures and it was believed that this could lead to bacteria endocarditis a severe infection of the lining of the chambers of the heart with a high mortality rate.  Until 2008 when National Institute for Health and Care Excellence (NICE) recommended that antibiotics were not required guidelines in many countries [read the full story…]