Periodontitis- supportive periodontal treatment


This Cochrane review of the effects of supportive periodontal therapy (SPT) in the maintenance of the dentition of adults treated for periodontitis included 4 RCTs providing is insufficient evidence to determine the superiority of different protocols or adjunctive strategies to improve tooth maintenance during SPT.

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Antidepressants for bipolar depression: weighing up the benefits and harms


Murtada Alsaif considers a recent systematic review on the safety and efficacy of adjunctive second-generation antidepressant therapy with a mood stabiliser or an atypical antipsychotic in acute bipolar depression.

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Adding antidepressants to antipsychotics in schizophrenia: do they work, for what, and are they safe?


Alex Langford explores the emerging findings from a recent meta-analysis looking at the efficacy and safety of antidepressants added to antipsychotics for people with schizophrenia and schizophrenia-like psychosis.

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Little research on non-surgical interventions to accelerate orthodontic treatment

iStock_000002551343XSmall colourful braces on teeth

With orthodontic treatment lasting typically 18-24 months, adjunts to accelerate tooth movements would be welcome. This Cochrane review identified two RCTs on non-surgical interventions to accelerate orthodontic treatment. However, both studies were at high risk of bias, so we cannot rely on their findings.

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