Results: 2606

For: systematic review

Combination therapies performed better than single ones for treating periodontal bony defects, but additional benefits were small

shutterstock_5410882 dentist x-ray

A range of regenerative treatments have been used for the  treatment of periodontal infrabony defects. Guided tissue regeneration (GTR) and enamel matrix derivatives (EMD) are two popular treatment and they have both been used in combination with other treatment.   This network meta-analysis was conducted to assess the potential effects of the various combinations. Unlike a [read the full story…]

The side effects of lithium: new systematic review provides toxicity profile

shutterstock_185880

Lithium is a medicine that has been used for over 50 years to treat depression and bipolar disorder. It comes in two forms that are used clinically: lithium carbonate and lithium citrate. A certain level of the drug is needed in the blood stream for it to be effective, but if the level rises too [read the full story…]

Robust studies needed to evaluate topical agents available to treat HIV related oral ulcers

Logo of The Cochrane Collaboration

HIV/AIDS is currently the leading cause of death in adults in Africa and the sixth leading cause of death worldwide. In HIV infected adults, oral ulcers occur more frequently, last longer, and produce more painful symptoms than in immunocompetent people.  The aim of this review was to evaluate the efficacy and side effects of topical [read the full story…]

The Geriatric Depression Scale is the best screening tool for depression in older people in acute hospital settings

shutterstock_86780905

Depression often occurs in later life and people in poor physical condition tend to be more susceptible than others. Older people in hospital who get depressed have poorer outcomes, so it’s important that we know how to detect depression and manage it in the acute setting. This systematic review conducted by researchers in Swansea set [read the full story…]

Bone substitutes with autogenous bone show similar short term results to autogenous bone alone for maxillary sinus floor elevation

shutterstock_5410882 dentist x-ray

Maxillary sinus floor elevation is commonly performed to create sufficient bone fraction to enable the placement of dental implants. The aim of this review was to assess the bone fraction and implant survival rate and to determine whether the bone fraction is affected by the grafting material or growth factor applied. The Medline and the [read the full story…]

GP training and guidelines implementation improves depression care, but training alone does not help, according to new systematic review

shutterstock_51805282

Healthcare providers are always on the look out for ways to improve the detection and diagnosis of depression in primary care. It’s a prevalent illness amongst Europeans with 6.9% of people suffering from it in any 12-month period. We know that 50-70% of depressed patients consult their GP during an episode, so improving systems for [read the full story…]

Limited evidence for the surgical management of temporomandibular joint ankylosis

shutterstock_36617959

Treatment for temporomandibular joint (TMJ) ankylosis include gap arthroplasty (GA) and resection of the ankylosis and reconstruction of the ramus–condyle unit with a costochondral graft or prosthetic joint. The aim of this review was to assess whether GA  or and resection of the ankylosis and reconstruction of the ramus–condyle unit with a costochondral graft produced [read the full story…]

No evidence that exercise referral schemes can increase physical activity, fitness or health outcomes for those with a medical diagnosis

shutterstock_3230116

We know that exercise helps people who are going through mental health difficulties, but how can we encourage people to become more active? Exercise referral schemes aim to identify inactive adults in the primary care setting. The GP or healthcare professional then refers the patient to a third-party service, with this service taking responsibility for [read the full story…]

Self-help interventions are effective treatments for social phobia and panic disorder, says new meta-analysis

shutterstock_26047456

The demand for psychological therapies far outstrips the supply and in this ongoing period of austerity we surely need to produce some cost-effective alternatives. One method that patients can attempt pretty much on their own is self-help provided through books, CDs, DVDs and websites. This new systematic review claims to be the first to bring [read the full story…]

Some evidence to support adjunctive amoxicillin and metronidazole for treatment of chronic periodontitis

shutterstock_29890228

Chronic periodontitis affects between 5-20% of the population. Scaling and root planing (SRP) is one of the most effective methods of treatment. The aim of this review was to assess whether  the adjunct of amoxicillin and metronidazole (AMX/MET) to SRP increased its effectiveness compared to SRP alone. The authors searched eight databases and hand-searched a [read the full story…]