The newer second-generation antipsychotic drugs (Risperidone, Quetiapine, Amisulpride, Aripiprazole, Clozapine, Olanzapine) are promoted because they have a lower risk of extrapyramidal side effects than older drugs. Drug companies often promote these newer drugs as virtually free from extrapyramidal side effects, but the patients who take them and the clinicians who prescribe them often don’t agree. [read the full story…]
More than 25% of patients with cleft lip and palate (CLP) develop hyperplasia of the maxilla that requires surgical correction. This surgery is usual occurs in the final phase of their CLP treatment and is typically a Le Fort I osteotomy. The aim of this review was to assess the long term stability of this [read the full story…]
Ooh, what a palaver over the depression and exercise story! Such a lot of words have been written about the study published in the BMJ last week, including by me. The study itself was well conducted but frankly disappointing (for us readers and the researchers themselves), finding as it did that a specific treatment to [read the full story…]
In 1998 a very small study was published, involving just 3 children with autism, who were treated with a hormone called secretin that controls digestion. Here’s the abstract of the study by Horvath et al: We report three children with autistic spectrum disorders who underwent upper gastrointestinal endoscopy and intravenous administration of secretin to stimulate [read the full story…]
Child sexual abuse is a widespread social problem, which can cause a range of mental health conditions including fear, anxiety, post-traumatic stress disorder, behavioural problems, inappropriate sexual behaviour and an increased risk of psychological problems in adulthood. Cognitive behavioural therapy is often used to help children (and their non-offending parent) to manage the conditions that [read the full story…]
Systemic and locally delivered antibiotics have been used as an adjunct to scaling and root planing (SRP) for the treatment of periodontal disease for many years. The aim of this review was to systematically evaluate the data concerning the effect of the concomitant administration of amoxicillin and metronidazole adjunctive to SRP in otherwise healthy adults. [read the full story…]
A certain amount of bone is required for the placement of dental implants and a range of techniques applied to reconstruct alveolar bone in order to place dental implants. The aim of this review was to assess the success rate of implants placed in horizontal and vertical guided bone regenerated (GBR) areas. What did they [read the full story…]
Endosseous root form dental implants have been available since the 1960s while dental Small-Diameter Implants were first introduced commercially in the dental field in 1990. The aim of this study was to determine, the survival of narrow diameter implants, whether survival is dependent on whether these implants are placed using a flap or flapless approach, [read the full story…]
The May issue of the Cochrane library sees another 3 dental protocols published:- Brocklehurst P, Tickle M, Birch S, Glenny AM, Mertz E, Grytten J. The effect of different methods of remuneration on the behaviour of primary care dentists (Protocol). Cochrane Database of Systematic Reviews 2012, Issue 5. Art. No.: CD009853. DOI: 10.1002/14651858.CD009853. This review [read the full story…]
A number of reviews have been published in recent years, which explore the prevalence of depression in old people. Prevalence rates vary enormously from one study to the next and so the reviews tend to report quite a wide range, typically up to 10%. Prevalence is defined as: “a measure of the proportion of people [read the full story…]
