Eight small trials were identified for this review of lasers as an adjunct to surgical periodontal treatment. The limited number of studies and variation in the types of lasers used means there is insufficient evidence to support their effectiveness.
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This review looked at topical fluoride for remineralising or arresting caries. 17 RCTs were included and overall remineralised early enamel caries using % fluoride varnish = 63.6 % (95% CI; 36.0 to 91.2 %) and 38% silver diamine fluoride had an overall proportion of arrested dentine caries = 65.9% (95% CI; 41.2 to 90.7 %).
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This study from the INHANCE collaboration pooled data from 12 case-controlled studies. Long-term use (35 yrs) of mouthwash was associated with an increase risk OR=1.15 (95%CI; 1.01 to 1.30) of head and neck cancer but with regular (>2 x daily), long-term (>35 years) use OR = 1.75 (95%CI; 1.25 to 2.48).
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This review includes 11 case-controlled and 4 cohort studies and suggests a 37% reduction of oral cancer risk in high coffee drinkers compared with low or no coffee drinkers OR= 0.63 (95%CI; 0.52 – 0.75)
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25 studies include 20 RCTs and 5 controlled trials were included this review. They were all conducted in a hospital or university setting and found that treatment duration was on average 19.9 months (95% CI; 19.58 to 20.22 months) over 17.81visits ( 95%CI; 19.71 to 20.32 months)
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The International Head and Neck Cancer Epidemiology (INHANCE) consortium is a collaboration of research groups leading large epidemiology studies to improve the understanding of the causes and mechanisms of head and neck cancer. This overview paper provides a summary their findings over the past decade.
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This review of the effectiveness of neem-based mouthwash for improving plaque control and gingival health only identified 3 low quality RCTs of short duration providing little evidence to assess its effectiveness.
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This Cochrane review update only identified 1 RCT assessing the difference in survival between bonded and non-bonded amalgam restorations providing insufficient evidence to support or refute a difference.
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This review of patient expectations of orthodontic treatment included 13 studies but found that the methodological quality was poor so recommended that future studies are needed based on well constructed theory.
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This review of the adjunctive use of amoxicillin and metronidazole with scaling and root planing for the management of periodontitis found improved clinical outcomes in terms of pocket depth and clinical attachment level with their use.
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