Polypharmacy is the simultaneous use of two or more drugs to treat a single health condition. Polypharmacy is often used in the treatment of schizophrenia where people are regularly prescribed two or more antipsychotics, as well as antidepressants and/or benzodiazepines, although there is little evidence to prove that these combinations are more effective than monotherapy. [read the full story…]
Weight gain is one of the side effects that people who take antipsychotic drugs complain of the most. Obesity is common in this population and this can often lead to cardiovascular problems and a far shorter life expectancy than the rest of the population. As a result, there is a great deal of interest in [read the full story…]
The possible link between the MMR vaccine and autism has been shown to have no basis in evidence, despite such a link being posited in a 1998 paper in the Lancet. The paper was subsequently retracted following a GMC investigation of its author. The researchers in this US study point out that although the link [read the full story…]
Following the media coverage of the NHS statistics published last week that reported a large rise in antidepressant prescribing, Martin Brunet (a GP from Surrey and author of the excellent Binscombe Doctor Blog) has written an opinion piece that explores the positive and negative aspects of this complex story: “Are GPs prescribing antidepressants too readily?” [read the full story…]
There are a range of treatment options for people with bipolar disorder who are experiencing a manic episode. An important part of this treatment is to reduce the symptoms of mania and provide the individual with some level of normality. I blogged this time last year about a meta-analysis in the Lancet that showed that [read the full story…]
The largest annual rise in prescriptions was seen in antidepressants according to figures published this week by the NHS Information Centre. 46.7 million prescriptions for antidepressants were dispensed in 2011, a rise of 3.9 million on 2010. This equates to a rise of 9.1% in the 12 month period, which is similar to that seen [read the full story…]
People with learning disabilities are often prescribed anti-psychotic medication, whether or not there has been a diagnosis of psychiatric disorder. There continues to be some concern about the evidence base to support this. The most recent Cochrane review which looked at the issue in relation to people with learning disabilities and schizophrenia found that there is [read the full story…]
Another week, another new type of publication from NICE. The local government public health briefings are aimed at local authorities and their partner organisations in the health and voluntary sectors, in particular those involved with health and wellbeing boards. Three briefings have been launched today on: Tobacco Physical activity Workplace health These briefings will be relevant [read the full story…]
Computerised cognitive behavioural therapy is a popular topic for research at the moment. We’ve seen a number of systematic reviews and large scale trials published over recent years, but the vast majority focus on adults with depression, so it’s hard to know how applicable the results are to adolescents. Of course, most young people are [read the full story…]
Citalopram (brand names: Cipramil and Celexa) is an antidepressant drug in the selective serotonin reuptake inhibitor (SSRI) class. It was one of the first SSRIs to come onto the market over 20 years ago and is available as tablets and as oral drops that are taken in a juice drink. There are lots of antidepressants [read the full story…]
