Results: 1711

For: Treatment

CBT may prevent depression in at-risk children whose parents have a history of depression

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The harmful impact of depression extends far beyond the individual sufferer to caregivers, friends and family members.  Children of people with depression are more likely to suffer from depression themselves.  This may be due to both inherited and environmental factors. This new randomised controlled trial (RCT), published earlier this week in JAMA Psychiatry, set out [read the full story…]

Insufficient evidence for effects of non-pharmacological interventions for the relief of dry mouth

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It has been estimated that between 10-26% of men and 10-33% of women experience dry mouth. The subjective sensation of dry mouth is called xerostomia and can be found in people with normal salivary gland function. The normal range of salivary production ranges from 0.5 to 1.5 litres per day.  The aim of this Cochrane [read the full story…]

Systematic review reveals conflicting evidence for relationship between diet and depression

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The question of what role nutrition plays in mental health has been the sauce (ahem) of research interest in recent times. As covered previously by oursElves in relation to dementia, the majority of this research has looked at individual nutrients like Omega-3 fish oil and other minerals, with the broader area of diet receiving less [read the full story…]

“Commissioners should ensure sustained and effective delivery of children’s palliative care” says guide

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Clinical Commissioning Groups, hospices, patients, carers, and all staff who provide palliative care to children. This short guide has been written for Clinical Commissioning Groups, hospices, patients, carers, and all staff who provide palliative care to children. Commissioners need to be aware that palliative care for children is very different to palliative care for adults, [read the full story…]

Moderators of outcome in late-life depression: should we be prescribing antidepressants to older people?

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Meta-analyses are an incredibly useful tool for synthesising evidence. However, such analyses typically use aggregate data, meaning the average scores or outcomes for treatment groups, which can cause problems if we’re trying to dig a little deeper into the question of ‘what works’ to answer ‘what works, and for whom?’ The ‘for whom?’ question is [read the full story…]

Atypical antipsychotics can lead to weight gain in children and adolescents, but more evidence needed about metabolic side effects

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Atypical (second-generation) antipsychotics are used to treat a variety of psychiatric conditions. Although they have fewer side effects than first-generation antipsychotics, weight gain and other metabolic problems (such as high blood pressure and diabetes) remain common side effects of taking atypical antipsychotic medication (Mind, 2012). The Mental Elf has previously blogged about a Canadian report [read the full story…]

Tricyclic antidepressants are associated with higher risk of bone fracture

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While most people would likely associate tricyclic antidepressants (TCAs) with more common adverse effects such as dry mouth, sedation and constipation, there is some evidence to suggest increased occurrence of bone fractures (Vestergaard, Rejnmark, & Mosekilde, 2006). However, the topic remains controversial and conflicting results about the association of TCAs and fracture risk abound (e.g. [read the full story…]

Can brain imaging help predict who will respond to CBT versus antidepressants?

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A major challenge in the treatment of depression is that only a proportion of people respond to the first treatment they try.  For example, with antidepressants only 40% of people will see their symptoms fall to a level that can be considered a recovery.  Trying further treatments after the first one does not work can [read the full story…]

NICE publish new Quality Standard and Evidence Update on ADHD

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Attention Deficit Hyperactivity Disorder (ADHD) is the most common behavioural disorder in the UK, with sufferers experiencing inattentiveness, hyperactivity, and impulsivity. It is estimated to affect 3-9% of school aged children and young people in the UK (those aged 3 to 18), and 2% of adults worldwide (DSM-IV criteria). Typically ADHD will continue from childhood [read the full story…]

35% of people with learning disabilities in Australian city prescribed psychotropic medications

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It is estimated that in UK, up to 200,000 people with learning disabilities are given anti-psychotic drugs, which can have powerful side effects, like risk of weight gain, impotence and strain to the cardiovascular system, and with little evidence of their efficacy in treating challenging behaviour. There are equal concerns about the use of anti-convulsant [read the full story…]