Zinc supplementation may be a useful add-on to treatment for depression

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There is evidence from epidemiological studies that low levels of zinc are associated with depression, but good quality clinical trials that explore the link between zinc supplementation and depression are few and far between. This systematic review conducted by a research team from the University of Newcastle in New South Wales, Australia, aimed to synthesise results from [read the full story…]

Is the PANSS (Positive and Negative Syndrome Scale) instrument for schizophrenia being used correctly?

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The PANSS (Positive and Negative Syndrome Scale) is one of the most important rating instruments for patients with schizophrenia. Kay’s original 1987 article on PANSS has been cited more than 4,000 times making it one of the most frequently cited schizophrenia articles on PubMed. Despite its common use there still seems to be profound uncertainty [read the full story…]

Group CBT is not cost-effective for treating postnatal depression

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The objective of this cost-utility analysis was to assess the cost-effectiveness of providing group cognitive-behavioural therapy (CBT), compared with routine primary care, for women with postnatal depression in the UK. Group CBT was compared with routine primary care for women with postnatal depression, defined by their Edinburgh Postnatal Depression Scale (EPDS) score, with scores ranging [read the full story…]

Community treatment orders for people with severe mental illness: do they work?

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There is controversy as to whether compulsory community treatment (known in the UK as community treatment orders) for people with severe mental illnesses reduces health service use, or improves clinical outcome and social functioning. Given the widespread use of such powers it is important to assess the effects of this type of legislation. Researchers from [read the full story…]

Are people with low levels of education at greater risk of dementia?

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The purpose of this systematic review was to explore the relationship between education and dementia. The authors from the University of Southern California searched PubMed and PsycInfo for published studies examining the relationship between education and dementia listed from January 1985 to July 2010. The inclusion criteria were a measure of education and a dementia [read the full story…]

Call for guidelines on role of physical conditions in challenging behaviour

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Physical factors can be a cause of some challenging behaviours in people with learning disabilities and this systematic review set out to determine what these conditions might be. The search covered the period 1990 and 2008and identified 45 studies. These looked at general medical conditions, motor impairment, epilepsy, sensory impairment, gastrointestinal disease, sleep disorders, dementia [read the full story…]

Self-guided psychological treatment has a small but significant impact on depression

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Self-guided psychological treatment is where a patient works through a programme of treatment without the aid of a therapist or coach.  There are now many Internet-based treatments for depression and anxiety and there have been a number of good quality trials published during the last few years on self-guided psychological treatments for depression. There have [read the full story…]

Motivational interviewing is better than doing nothing for people with drug and alcohol problems

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More than 76 million people worldwide have alcohol problems, and another 15 million have drug problems. Motivational interviewing (MI) is a psychological treatment that aims to help people cut down or stop using drugs and alcohol. The drug abuser and counsellor typically meet between one and four times for about one hour each time. The [read the full story…]

Psychoeducation seems to reduce relapse, readmission and encourage medication compliance for people with schizophrenia

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Schizophrenia can be a severe and chronic illness characterised by lack of insight and poor compliance with treatment. Psychoeducational approaches have been developed to increase patients’ knowledge of, and insight into, their illness and its treatment. It is supposed that this increased knowledge and insight will enable people with schizophrenia to cope in a more [read the full story…]

Depot antipsychotic drugs may reduce relapse in patients with schizophrenia

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Many people with schizophrenia struggle to adhere to their oral antipsychotic drug regimen.  It is thought that depot antipsychotic drugs (a special preparation of the medication, which is given by injection and is slowly released into the body over a number of weeks) may reduce relapse rates by improving adherence. This systematic review searched for randomised controlled [read the full story…]