Extraction vs non-extraction of premolars for orthodontic treatment

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This scoping review of the literature comparing orthodontic treatment undertaken with and without the extraction of premolar teeth included 399 articles. Most study reports were of low methodological quality, and further reviews are unlikely to provide new information. Researchers should focus on high quality prospective primary studies that include outcomes of imortance to patients.

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Non‐surgical procedures to accelerate orthodontic tooth movement

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This Cochrane review update was to assess the effect of non‐surgical adjunctive interventions on the rate of orthodontic tooth movement and the overall duration of treatment included 23 RCTs.The findings suggest there may be limited benefit from photobiomodulation application for accelerating discrete treatment phases but this should be interpreted very cautiously as the findings may not be clinically important and the evidence is of low to very low certainty.

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Orthodontically induced external apical root resorption

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This review comparing orthodontically induced external apical root resorption (EARR) in root-filled teeth and vital pulp teeth included 11 mainly retrospective studies . The findings suggest less EARR in root-filled teeth but the evidence is of very low certainty.

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Malocclusion and quality of life

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This review of the effect of malocclusion on oral health-related quality of life in adolescents includes 13 cross-sectional studies. The findings suggest that that malocclusions in adolescents have a negative impact on oral health-related quality of life (OHRQoL).

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White spot lesions – treatment options

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This review and network meta-analysis of seven treatments for white spot lesions (WSLs) included 36 clinical RCTs published since 2007. The findings suggest that self-assembling peptide P11-4 and resin infiltration had a positive effect on WSLs but the findings should be interpreted cautiously.

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Orthodontic retainers and retention strategies

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This Cochrane review update evaluating different retention strategies used to stabilise tooth position after orthodontic braces included 47 RCTs. However, only 11 RCTs were at low risk of bias and the overall assessment of the certainty of the evidence is low to very low which means that firm recommendations on orthodontic retention strategies cannot be made.

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Orthodontic bonding – failure rates with different techniques

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This review of the failure rates of different orthodontic bonding materials included 80 studies with 34 contributing to the quantitative component. The findings suggest little difference between the self-etch primer and conventional acid-etch primer and a poorer performance for glass ionomer compared with self-cure resin. However the findings should be interpreted cautiously because of the low certainty of the available evidence.

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Anterior open bite self-correction after cessation of non-nutritive sucking habits

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This review of whether self-correction of anterior open bite (AOB) occurred after stopping non-nutritive sucking habits after 4 years of age included 5 studies. The studies reported a range of self-correction of AOB from 50-100% however the studies were all at high risk of bias providing evidence of very low certainty.

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Adjunctive chlorhexidine for gingival health in orthodontic patients

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This review of the efficacy of chlorhexidine (CHX) products in maintaining gingival health in orthodontic patients with fixed appliances included 20 RCTs only 1 of which was at low risk of bias. The findings showed a benefcial effect on gingival parameters with CHX mouthwash at 1-3 months but the findings should be interpreted cautiously.

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Fluoride varnish for prevention of white spot lesions during orthodontic treatment

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This review evaluating the preventive effect of regular applications of fluoride varnish (FV) on the development of white spot lesions (WSL) during orthodontic treatment included 7 RCTs. Meta-analyses demonstrated a reduction in the risk of WSL with regular FV applications but the certainty of evidence was very low.

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