New evidence on treatments for symptoms of depression in dementia


Andrew Sommerlad appraises a recent review on the efficacy of interventions for depression in people with dementia, which identified several non-drug treatments that can have a meaningful effect on depressive symptoms in dementia.

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Antidepressants for depression in Alzheimer’s Disease


The EQUATOR Publication School #EQPubSchool group summarise a systematic review and meta-analysis on the efficacy of antidepressants for depression in Alzheimer’s Disease, which finds no statistical difference between antidepressants and placebo.

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New RCT says antidepressants should not be used when treating depression in dementia

Senior woman taking pill

Dementia is one of the most common and serious disorders in later life. It places a considerable burden on the health care system, individuals and especially unpaid carers. Depression is common among people with dementia and causes additional distress to affected individuals and their social circle. Research into the treatment of depression in dementia is [read the full story…]

Scotland sees increase in prescribing rates for mental health drugs


The Scottish Government have published their annual summary of prescribing statistics for mental health drugs. The report shows increases in the prescribing rates for all groups of drugs over the last 12 months. The prescribing costs of some groups of drugs have also risen (ADHD, dementia, depression) although other groups have seen a decline (insomnia [read the full story…]

Depression in later life: new clinical review from the BMJ


This week’s British Medical Journal features a review of depression in later life. The authors bring together recent systematic reviews, meta-analyses, and randomised controlled trials to summarise best current knowledge about the diagnosis and management of patients who develop depression in later life. The review addresses the following questions: What is late life depression and [read the full story…]

Sertraline and mirtazapine do more harm than good for people with dementia and depression


Depression is common in patients with dementia and antidepressants are widely prescribed for this population although the evidence remains limited. This randomised controlled trial conducted by researchers at the Institute of Psychiatry in London and published in the Lancet, explored the safety and efficacy of two widely-used drugs (sertraline and mirtazapine) in patients with dementia and [read the full story…]