Rapid weight gain after SMI diagnosis, but why so few referrals for support?

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A 15-year analysis of UK primary care records showed steep and sustained weight gain after an SMI diagnosis, especially among younger adults and people prescribed antipsychotic medication. Yet very few received referrals for weight-management support, raising important questions about practice and policy.

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A cancer diagnosis brings a suicide risk: The sooner after diagnosis, and the more aggressive the cancer, the higher the risk

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Does a first cancer diagnosis increase a person’s risk of suicide? This national study from Denmark offers rare clarity, tracking 30 cancer types across two decades to uncover patterns that clinicians and policymakers cannot afford to ignore.

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Recovery, relapse, and genetic risk: what 10,000 Danes taught us about eating disorder trajectories

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How often do people with eating disorders switch diagnoses, recover, or relapse? This large Danish study follows more than 10,000 people over nearly a decade, uncovering patterns of remission and genetic vulnerability that could help shape more personalised care.

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Mind the age gap: Young adults may benefit less from NHS psychological therapies

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If NHS Talking Therapies work so well, why are recovery rates lower for young adults? Saunders and colleagues analysed data from 1.5 million people to find out, and the results show an urgent need to rethink how we support young people in distress.

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Do hobbies protect against adolescent substance misuse? Not so fast…

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A new study claims hobbies reduce substance misuse in adolescents, but are we mistaking correlation for causation? Before we start fiddling with interventions, this blog explores the risks of jumping to conclusions.

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suPAR step forward? Teenage trauma linked to chronic inflammation in new study

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Not all childhood trauma has the same biological impact. A new study finds that adversity in late childhood is most strongly linked to immune dysregulation at age 24.

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Adolescent versus adult depression: Is risk of recurrence the same?

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Is teenage depression more likely to come back later in life? A new population study challenges assumptions and finds similar recurrence risks in both adolescents and adults.

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Clozapine and infection risk: new evidence from Hong Kong’s 20-year cohort study

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Clozapine is described as the gold standard treatment for schizophrenia but a new cohort study suggests it is associated with an increased risk of infections, particularly in older patients, further solidifying the case for holistic care.

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Unravelling bipolar disorder: insights from the biggest genetic study to date

Bipolar disorder is a leading contributor to the global burden of disease with significant impact on quality of life, functioning and suicide risk.

A massive new multi-ancestry genetic study of bipolar disorder has uncovered hundreds of risk loci and highlighted biological pathways that may guide more precise treatments and prevention strategies in the future.

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Teen drug use today, mental health struggles tomorrow? What the evidence says

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Ian Hamilton unpacks a new study revealing how teenage substance use can pave the way to serious mental health struggles later in life. A clear warning: early use today could mean bigger problems tomorrow.

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