Periodontitis: evidence lacking for different cytokine/chemokine profiles in aggressive and chronic disease

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This review included 17 studies and 843 patients. A wide range of cytokines/chemokines were assessed but the available evidence is not sufficient to prove that there are distinct differences between patients with aggressive periodontitis and those with chronic periodontitis.

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Chronic periodontitis: review suggests that Er:YAG laser may provide short term improvement

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This review compares the clinical outcomes of scaling and root planing with Er:YAG laser either as an alternative or as an adjuvant in patients with chronic periodontitis. 12 small trials were included and similar outcomes were seen with both treatments at 3 months . However hetrogeneity in teh studies and the small sample size mean that these finding should be interpreted with caution.

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Review suggests small benefits from enamel matrix derivative in the treatment of periodontal pockets of suprabony defects

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A number of different regenerative techniques, guided tissue regeneration (GTR), bone grafting (BG) and the use of enamel matrix derivative (EMD) have been used to try and regenerate periodontal tissues. The aim of this review was to assess the effectiveness of EMD in the treatment of periodontal pockets of suprabony defects. Searches were conducted in [read the full story…]

Cost effectiveness of surgery versus root planing in patients with chronic periodontitis

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Both surgical and non-surgical approaches can be used for the treatment of chronic periodontitis. The traditional approach being improving plaque control and non- surgical scaling and root planing (SRP) followed by surgical re-treatment where indicated. The main aim of this study was to compare immediate surgery with SRP in the treatment of advanced periodontal disease [read the full story…]

ADA-EBD summary on amoxicillin/metronidazole therapy for chronic periodontitis

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This ADA-EBD critical summary  looks at  systematic review by Sgolastra et al from 2012 that addressed  the question of whether the use of amoxicillin/metronidazole (AMX/MET)  as an adjunct to scaling and root planning (SRP) was more effective than SRP alone in the treatment of chronic periodontitis. The appraisers considered that searching an analysis of the [read the full story…]

Critical summary from the American Dental Association Center for Evidence-based Dentistry

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The ADA-EBD Center has just published another of its critical summaries of systematic reviews.  This one looks at a 2012 review by Sgolastra et al, which was looking at the efficacy of the Er:YAG laser when used as an alternative treatment to scaling and root planing (SRP) in the treatment of patients with chronic periodontitis? [read the full story…]

Limited information on the effects of smoking cessation on clinical outcomes following periodontal therapy

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Limited information on the effects of smoking cessation on clinical outcomes following periodontal therapy Smoking is a known risk factor for periodontal disease. The aim of this study was to conduct an individual patient data meta-analysis to assess the effect of smoking cessation (SC) on clinical outcomes following the non-surgical periodontal treatment in patients with [read the full story…]

Review suggests that antimicrobial photodynamic therapy may provide additional benefit to scaling and root planning for patients with chronic periodontitis

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The aim of this review was to evaluate the clinical adjunctive effect of antimicrobial photodynamic therapy (aPDT) to scaling and root planing (SRP) when compared with SRP alone or in combination with placebo in the treatment of chronic periodontitis (CP) patients. A search in the Medline, Cochrane Controlled Clinical Trial Register, Cochrane Database of Systematic [read the full story…]

Weak evidence suggests small additional benefit from the use of local antimicrobials as adjunct to scaling and root planning for chronic periodontitis patients

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Scaling and root planning (SRP) is the main therapeutic approach to treating periodontitis. The adjunctive use of local antimicrobials has demonstrated some improvement in outcomes.  The aim of this review was to assess the effect on clinical outcomes of local antimicrobials as adjuncts to SRP, compared to SRP alone or plus placebo, in chronic periodontitis [read the full story…]

Trail shows improved outcomes with metronidazole alone or with amoxicillin as adjuncts to non-surgical treatment of chronic periodontitis

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The main aim of this study was to evaluate the effects of the adjunctive use of metronidazole (MTZ) or MTZ + amoxicillin (AMX) in the treatment of generalized chronic periodontitis (ChP). Participants with untreated generalized ChP were randomised to receive either scaling and root planning (SRP) only (n= 40); SRP with MTZ, 400 mg/3 times [read the full story…]