Psychiatric disorders are highly heritable, but are the genes we identify in GWAS the same ones our medications target? This new study digs into the overlap and raises questions about how we develop treatments.
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This pilot study explored how a ketogenic diet affects mood, metabolic health, and brain chemistry in people with bipolar disorder. The results are early, but they offer food for thought.
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CBT is a cornerstone of mental health care, but how well does it really work across different disorders? This massive new meta-analysis offers some answers and raises new questions.
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A massive new multi-ancestry genetic study of bipolar disorder has uncovered hundreds of risk loci and highlighted biological pathways that may guide more precise treatments and prevention strategies in the future.
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Risk of respiratory disease is greatly heightened for people with bipolar disorder but we are missing opportunities to intervene to improve lung health.
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Shuichi Suetani and Melanie Johnston review new data on the prevalence of psychiatric conditions for people with intellectual and developmental disabilities. How can psychiatrists support person-centred care for those with intellectual disabilities?
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Alyson Dodd reports on a year long study of digital mood monitoring in people with bipolar disorder, which suggests that sleep and activity changes precede hypomanic episodes by three days. This data could be a useful clinical tool, but more research is needed.
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Mary Butler explores a recent randomised controlled trial of probiotic formulations for patients with bipolar disorder or schizophrenia spectrum disorder.
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Emiliana Tonini looks at how sleep is recorded and treated in people with serious mental illness—and how it affects their engagement with services. The study finds that sleep is rarely part of routine clinical assessment, and recommended sleep treatments are hardly ever used.
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This Swedish cohort study, blogged by Duncan Swiffen, is yet more evidence for lithium as an excellent treatment for people with bipolar disorder. This time it comes out on top in terms of preventing depression-related hospitalisation.
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