We know that many people who take antipsychotic drugs find it difficult to cope with the side effects of the medication and this often leads to them stopping their treatment. This large Finish cohort study examines the risks of rehospitalisation and drug discontinuation in patients recently diagnosed with schizophrenia who have been prescribed antipsychotics. The [read the full story…]
A systematic review has identified 106 potential risk factors to be associated with the prevalence or incidence of dental caries in primary teeth. The aim of this study was to describe the development of new caries over 2 years and to identify risk factors that can predict new caries development. A random sample of preschool [read the full story…]
There are a number of cross-sectional studies that investigate antidepressant use in teenagers and young adults. These are interesting, but because they don’t tend to follow-up study participants prospectively over a long period of time, there is only so much we can learn from them. However, now researchers in Finland have published a study that [read the full story…]
This cohort study conducted by researchers from the St. Louis Veterans Affairs Medical Center set out to answer the question: Are antidepressants associated with an increased or decreased risk of incident myocardial infarction and all-cause mortality? 93,653 patients aged 25–80 years (average age 51.5 years, 14.1% female, 77.8% White, 57.1% not married) were identified using the [read the full story…]
The hormone oestrogen could play an important role in late-life depression, according to new research published in the August issue of the British Journal of Psychiatry. Oestrogen is best known as one of the significant hormones in reproduction. It is also believed to have a part to play in mood and mental health, because of [read the full story…]
This cohort study of 327 oral lichen planus (OLP) patients; 229 women (70.0%) and 98 men (30.0%), was conducted using data from a cohort of caucasian patients from Italy with clinical and pathologic diagnosis of OLP, according to revised and modified World Health Organization diagnostic criteria. Follow-up of the patient cohort was started 6 months [read the full story…]
The aims of the study were to determine how frequently oral potentially malignant disorders (OPMDs) transform to cancer and to identify clinical and histological factors determining the rates of transformation. The study cohort included 1357 patients with biopsy-confirmed OPMDs seen at Guy’s Hospital between 1990 and 1999 and followed up until 2005. The patients’ details [read the full story…]
This large cohort study looked at whether depression is a risk factor of temporomandibular disorder (TMD). The study used claims data from The National Health Insurance program of Taiwan which covers more than 96% of its 23 million population. From the database 7,587 patients who are newly diagnosed individuals with depression and 30,197 comparison subjects [read the full story…]
This cohort study conducted by the Intensive Medicines Monitoring Programme (IMMP) in New Zealand, set out to determine more accurately the rates of nocturnal enuresis in patients on clozapine and other atypical antipsychotics (olanzapine, quetiapine and risperidone). Prescription data for clozapine, olanzapine, risperidone and quetiapine were returned from pharmacies throughout New Zealand directly to the [read the full story…]
Previous studies have reported that the use of applied behaviour analysis by a specialist team in addition to standard treatment for adults with learning disabilities and challenging behaviour was both clinically effective and cost-effective after 6 months. This study reported a 2-year follow-up of the same trial cohort. The study found that participants who were [read the full story…]
