Results: 435

For: risk factors

The genetic link behind sleep problems, cognitive dysfunction, and neuroticism in ‘treatment-resistant depression’

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A big new study suggests that certain genetic traits—like insomnia risk and neuroticism—may make depression harder to treat, while protective traits include education and cognitive ability.

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Prevention in name only: Are national dementia plans delivering on their promises?

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With dementia rates rising fast, prevention is critical. But do countries’ plans reflect that urgency? This new paper analyses 16 national dementia strategies—and finds good intentions often aren’t backed by clear actions.

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The scars that shape the mind: childhood adversity and the risk of psychosis

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Emotional abuse in childhood was linked to a more than 3.5x greater chance of developing psychosis later in life. This comprehensive new meta-analysis explores the role of early trauma, sex differences, and symptom onset timing in psychosis risk.

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Cannabis, psychosis and the structural realities for ethnic minorities

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KCL MSc student Geetika Sharma reviews a study that looks at the contribution of cannabis use to the increased psychosis risk among minority ethnic groups in Europe.

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Are circadian rhythms the key to understanding our physical and mental health?

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Amy Ferguson discusses the latest research exploring the role of our circadian rhythms on our health, looking at different variants in the BMAL1 gene.

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The Venn diagram of psychosis, developmental trauma and dissociation

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Kirsten Lawson reviews a pair of papers looking at the interplay between developmental trauma, dissociation and psychosis, which suggest that dissociation may act as a mediator between developmental trauma and psychosis.

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Age-at-migration and ethnicity may increase psychosis risk

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Sueda Coskun reflects on a recent case control study with data from five European countries, which suggests that migration during adolescence may be a particular risk factor for developing psychosis.

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Cannabis legalisation: what can we learn about psychosis risk from the great Canadian (quasi) experiment?

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What happens to psychosis risk when cannabis becomes easier to access? According to this Canadian study, the risk goes up. Shuichi Suetani explores what we can learn from one of the countries leading the way in drug policy reform.

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Hormonal coil dosage and depression risk

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Dr Rachel Reid-McCann discusses the latest research on dosage of levonorgestrel-releasing intrauterine system (LNG-IUS) and the risk of depression. A well conducted study from Denmark “provides evidence of a dose-dependent association between LNG exposure and risk of subsequent depression across three dosages”.

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The genetic relationship between ADHD and depression

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Tim van der Es discusses a recent paper that investigates whether ADHD causally increases the risk of subsequent major depression diagnoses. The study findings underscore the need for effective treatment and assessment of ADHD and a requirement for a deeper understanding of the potential causal mechanisms linking ADHD and depression.

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