Sjögren’s syndrome: treatments for dry mouth and hyposalivation

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36 studies were included in this review of treatment options for xerostomia, hyposalivation and quality of life in patients with Sjögren’s syndrome provinding evidence to support pilocarpine use. However the number of studies were limited and adverse effects were common.

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No strong evidence for any topical treatments for relieving the symptoms of dry mouth

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The subjective sensation of dry mouth or xerostomia is a common symptom and estimates of the prevalence vary from 10-50%.  The Cochrane Collaboration published systematic  of topical treatments for reducing the effects of dry mouth in 2011(Furness et al). Recently the American Dental Association’s Evidence-based Dentistry Center have published a critical summary of this review [read the full story…]

No strong evidence that any topical treatment is effective for relieving the sensation of dry mouth

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The prevalence of persistent dry mouth varies but a conservative estimates is that about 20% in the general population, with increased prevalence in women (up to 30%) and in the elderly (up to 50%). The aim of this Cochrane review was to determine which topical treatments for dry mouth are effective in reducing this symptom. [read the full story…]