Systemic antibiotics for aggressive periodontitis?

shutterstock_113989924  - periodontitis

This review of systemic antibiotics and non-surgical periodontal therapy for aggressive periodontitis included 13 RCTs and suggests a statistically significant benefit compared to non-surgical therapy alone.

[read the full story...]

Aggressive periodontitis: systemic antibiotics may improve outcome


This review and network meta-analysis included 11 small RCTs of limited quality, suggesting a statistically significant benefit for the use of adjunctive systemic antibiotics for the treatment of aggressive periodontitis.

[read the full story...]

Non-surgical periodontal treatment – is there a role for systemic antibiotics?


This review update includes 23 new studies comparing the effects of antibiotic therapy adjunctive to scaling and root planning for periodontal disease. While some additional benefit was shown the authors could not establish definitive conclusions and guidelines regarding their use.

[read the full story...]

ADA-EBD summary on amoxicillin/metronidazole therapy for aggressive periodontitis


This ADA-EBD critical summary looks at a systematic review from the same group that conducted the review that we highlighted yesterday (Sgolastra et al 2012).  This time the question was whether the use of amoxicillin/metronidazole (AMX/MET) as an adjunct to scaling and root planning (SRP) was more effective than SRP alone in the treatment of [read the full story…]

Latest critical summaries from the American Dental Association Center for Evidence-based Dentistry


Two new critical summaries are now available from the ADA-EBD website. First is a summary of a 2012 systematic review by Zandbergen et al that looked the systemic administration of amoxicillin and metronidazole as an adjunct to scaling and root planning (Dental Elf 25th May 2012). The review notes that there was no comparison in [read the full story…]

Trail shows improved outcomes with metronidazole alone or with amoxicillin as adjuncts to non-surgical treatment of chronic periodontitis


The main aim of this study was to evaluate the effects of the adjunctive use of metronidazole (MTZ) or MTZ + amoxicillin (AMX) in the treatment of generalized chronic periodontitis (ChP). Participants with untreated generalized ChP were randomised to receive either scaling and root planning (SRP) only (n= 40); SRP with MTZ, 400 mg/3 times [read the full story…]

Systemic antibiotics as an adjunct to non-surgical periodontal treatment


Systemic and locally delivered antibiotics have been used as an adjunct to scaling and root planing (SRP) for the treatment of periodontal disease for many years. The aim of this review was to systematically evaluate the data concerning the effect of the concomitant administration of amoxicillin and metronidazole adjunctive to SRP in otherwise healthy adults. [read the full story…]

Better outcomes with metronidazole and amoxicillin as an adjunct to full mouth disinfection for patients with aggressive periodontitis

shutterstock_2092494 Dentist and assistant are examining you the patient

About 1 in 1000 susceptible patients suffers from aggressive periodontitis. Sufferers have more rapid  gingival attachment loss with some losing more that half their bony support by 35. This can be localised  to a small number of teeth or more generalised.  The aim of this study was to evaluate the adjunctive clinical and microbiological effects [read the full story…]

Some evidence to support adjunctive amoxicillin and metronidazole for treatment of chronic periodontitis


Chronic periodontitis affects between 5-20% of the population. Scaling and root planing (SRP) is one of the most effective methods of treatment. The aim of this review was to assess whether  the adjunct of amoxicillin and metronidazole (AMX/MET) to SRP increased its effectiveness compared to SRP alone. The authors searched eight databases and hand-searched a [read the full story…]