Periodontal treatment- adjuvant antibiotics for diabetic patients?

shutterstock_2584741

This review of adjuvant antibiotics for diabetics undergoing periodontal treatment included 13 small RCTs. While a statistically significant improvement in probing depth was seen the magnitude of this improvement is unlikely to be clinically significant.

[read the full story...]

Amoxicillin and metronidazole as an adjunct to scaling and root planning for periodontitis?

shutterstock_2584741

This review of the adjunctive use of amoxicillin and metronidazole with scaling and root planing for the management of periodontitis found improved clinical outcomes in terms of pocket depth and clinical attachment level with their use.

[read the full story...]

Third molars: single dose of preoperative antibiotic reduced infection

shutterstock_31846396

10 RCTs were included in this review of preoperative antibiotics for removal of third molars. The use of antibiotics significantly reduced the odds of surgical site infection or alveolar osteitis (OR = 0.30; 95% CI, 0.19 to 0.47; P≤.00001)

[read the full story...]

Systemic antibiotics for aggressive periodontitis?

shutterstock_113989924  - periodontitis

This review of systemic antibiotics and non-surgical periodontal therapy for aggressive periodontitis included 13 RCTs and suggests a statistically significant benefit compared to non-surgical therapy alone.

[read the full story...]

Aggressive periodontitis: systemic antibiotics may improve outcome

shutterstock_70250746

This review and network meta-analysis included 11 small RCTs of limited quality, suggesting a statistically significant benefit for the use of adjunctive systemic antibiotics for the treatment of aggressive periodontitis.

[read the full story...]

Non-surgical periodontal treatment – is there a role for systemic antibiotics?

shutterstock_138231533

This review update includes 23 new studies comparing the effects of antibiotic therapy adjunctive to scaling and root planning for periodontal disease. While some additional benefit was shown the authors could not establish definitive conclusions and guidelines regarding their use.

[read the full story...]

ADA-EBD summary on amoxicillin/metronidazole therapy for aggressive periodontitis

shutterstock_28627237

This ADA-EBD critical summary looks at a systematic review from the same group that conducted the review that we highlighted yesterday (Sgolastra et al 2012).  This time the question was whether the use of amoxicillin/metronidazole (AMX/MET) as an adjunct to scaling and root planning (SRP) was more effective than SRP alone in the treatment of [read the full story…]

Latest critical summaries from the American Dental Association Center for Evidence-based Dentistry

shutterstock_73917457

Two new critical summaries are now available from the ADA-EBD website. First is a summary of a 2012 systematic review by Zandbergen et al that looked the systemic administration of amoxicillin and metronidazole as an adjunct to scaling and root planning (Dental Elf 25th May 2012). The review notes that there was no comparison in [read the full story…]

Trail shows improved outcomes with metronidazole alone or with amoxicillin as adjuncts to non-surgical treatment of chronic periodontitis

shutterstock_77485570

The main aim of this study was to evaluate the effects of the adjunctive use of metronidazole (MTZ) or MTZ + amoxicillin (AMX) in the treatment of generalized chronic periodontitis (ChP). Participants with untreated generalized ChP were randomised to receive either scaling and root planning (SRP) only (n= 40); SRP with MTZ, 400 mg/3 times [read the full story…]

Systemic antibiotics as an adjunct to non-surgical periodontal treatment

shutterstock_70250746

Systemic and locally delivered antibiotics have been used as an adjunct to scaling and root planing (SRP) for the treatment of periodontal disease for many years. The aim of this review was to systematically evaluate the data concerning the effect of the concomitant administration of amoxicillin and metronidazole adjunctive to SRP in otherwise healthy adults. [read the full story…]