Little good evidence currently available to support the effectiveness of antidepressants in the treatment of orofacial pain

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Orofacial pain is a relatively common and is categorized into musculoskeletal; neuropathic; vascular; neurovascular; idiopathic; pain caused by local, distant, or systemic pathology; and psychogenic.  Diagnosis can be challenging when psychosocial factors are present and while antidepressants have been used as a treatment there remains some controversy.  The aim of this review was to assess [read the full story…]