Young people with psychotic symptoms should be offered CBT before antipsychotics, according to new RCT

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Antipsychotic drugs are currently prescribed to a significant proportion of young people who are diagnosed with psychosis. Past research has estimated that up to half of people at risk of developing psychosis at a young age will progress to a full blown psychotic illness such as schizophrenia. A new landmark randomised controlled trial has been [read the full story…]

New systematic review shows how the incidence of schizophrenia and other psychoses has changed since 1950

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This is one in a series of 5 systematic reviews commissioned by the Department of Health, which seek to establish a comprehensive understanding of the distribution and pattern of psychotic disorders in England, between 1950 and 2009. All mental health professionals, commissioners and health planners will find this research relevant to their work. It’s well [read the full story…]

Cholinesterase inhibitors are an effective treatment for patients with Parkinson’s disease with dementia

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People with Alzheimer’s disease experience a loss of nerve cells that use a chemical called acetylcholine as a chemical messenger. Dementia symptoms become more severe as more nerve cells are lost. Cholinesterase inhibitors are a group of drugs (including donepezil, rivastigmine and galantamine) that prevent the enzyme acetylcholinesterase from breaking down acetylcholine in the brain. [read the full story…]

Targeted psychotherapies work best for children and adolescents with anxiety disorders, according to major new meta-analysis

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Around 10% of children are diagnosed with anxiety disorders before the age of 16 and for many this can be a long lasting problem that has a major impact on their development. There’s lots of research in this field and many systematic reviews have been conducted to assess the effectiveness of talking treatments for this [read the full story…]

Insufficient evidence to recommend first line treatment for depression in cancer patients

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Depression is at least three times as common in patients with cancer compared to the rest of the population. Studies show that major depression occurs in 16% of cancer patients, with combined minor depression and dysthymia reported in 22% of people with cancer. Depression also appears to be more prevalent amongst people with certain cancers (pancreatic, [read the full story…]

Life skills programmes are no better than standard care or support groups for people with chronic mental illness

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People with chronic mental illnesses such as schizophrenia often struggle to cope with the basic tasks that life throws at them. Their health condition and the often debilitating effects of medication can make simple things like going to the shop or cleaning the house almost insurmountable hurdles. Various rehabilitation therapies are used to help people [read the full story…]

WHO guidelines for mental, neurological and substance use disorders in low- and middle-income countries

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The World Health Organization’s Mental Health Gap Action Programme (mhGAP) aims to tackle mental, neurological and substance use disorders in low- and middle-income countries. 14% of the global burden of disease is made up by these disorders and many people do not have access to the treatments they need. The programme asserts that with proper [read the full story…]

Lifestyle education can help people with diabetes and schizophrenia lose weight, according to new systematic review

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For many different reasons, people with schizophrenia and schizoaffective disorders have a greater risk of type 2 diabetes.  The prevalence of type 2 diabetes in people with schizophrenia is twice that of the general population. This review looked for evidence of the efficacy of interventions to help people with schizophrenia manage their diabetes. Clinical question [read the full story…]

Rethinking physical activity for depression: what’s cost effective?

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Exercise is a good thing right? It seems obvious that people who are affected by mental health problems would benefit from getting themselves outside and becoming more active, but are these ‘treatments’ value for money when they are delivered in a structured way? The current NICE depression guideline recommends ‘structured’ physical activity programmes for depression [read the full story…]