Depressed patients who respond poorly to antidepressants are significantly more likely to develop bipolar disorder, says new cohort study

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Bipolar disorder is a complex health condition and the diagnosis of bipolar depression is a fairly contentious topic. This is because depression occurs in bipolar disorder alongside a wide range of symptoms of mood elevation. Some patients have depressive episodes as well as severely elevated mood during the course of their illness, whereas other patients [read the full story…]

Moving towards evidence-based drug policy: new paper in the Lancet

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Evidence-based drug policy is a phrase you don’t read that often. Many searches for this phrase return articles that explore why we don’t have evidence-based policies for illicit drugs and why the evidence base is weak in this area. A group of international researchers and policy makers (including two UK-based professionals) are trying to buck [read the full story…]

Memantine is not an effective treatment for dementia in people with Down’s syndrome, according to new RCT

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People with Down’s syndrome are more likely to develop dementia than others and one in three will have the illness as early as in their 50s. Despite this high prevalence, there is very little reliable research about drug treatments for this population. This small randomised controlled trial (funded by the drug company Lundbeck) aimed to [read the full story…]

More psychotherapy does not improve social functioning for depressed people also taking antidepressants

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This is an unusual randomised controlled trial conducted by a research team from Arkin Institute for Mental Health in Amsterdam and funded by Eli Lilly. The study measures social functioning as an outcome, as well as the more commonly measured depression symptoms. It aims to find out how much psychotherapy is optimal for depressed people [read the full story…]

Adding CBT to drug therapy helps children with OCD who don’t respond to antidepressants alone

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Obsessive compulsive disorder (OCD) is a condition that is usually associated with obsessive thoughts and compulsive behaviour. It’s one of the most common mental health problems in young people, with an estimated 5% of children and teenagers suffering from the chronic condition. Studies have shown that SSRI antidepressants and cognitive behavioural therapy (CBT) are both [read the full story…]

New report from the Alzheimer’s Society makes recommendations for the commissioning of dementia services

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Mental health commissioners will be interested in this new report from the Alzheimer’s Society and MHP Health Mandate, that was published just before Christmas.  It follows on from the publication of the Department of Health’s Dementia Commissioning Pack back in July 2011. The report looks at the current policy landscape and how it relates to [read the full story…]

New guideline on the diagnosis and treatment of eating disorders

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The 8 year old NICE guideline on eating disorders should be updated fairly soon. In the meantime, researchers in Germany have published a new clinical practice guideline on anorexia nervosa, bulimia nervosa and binge eating disorder. The guideline contains evidence- and consensus-based recommendations for the diagnosis and treatment of eating disorders. The guideline is available in [read the full story…]

Mental illness following childbirth can help predict bipolar disorder in later life

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We know that it can take many years for people with bipolar disorder to be accurately diagnosed, following an initial episode of mental illness. This cohort study carried out by researchers from Denmark, the US and Wales, set out to study to what extent psychiatric disorders with postpartum onset (following childbirth) are early manifestations of [read the full story…]

Trauma-focused cognitive behavioural therapy may help young children with post traumatic stress disorder

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Recent studies have shown that pre-school children can be affected by post traumatic stress disorder (PTSD) and that the condition can last for years even after treatment. Good quality randomised trials have shown that trauma-focused cognitive behavioural therapy can be a very effective treatment for older children and adolescents with PTSD, but there have been [read the full story…]

Happy Christmas to all Mental Elf readers and followers!

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We elves have a busy time of it over the festive period, what with the present-wrapping, gift-giving, evidence-sifting and blogging.  It’s a wonder we don’t become crippled by stress and end up completely Christmas crackers. I’m taking a few days off over the holiday period to unwind and relax in the woods with my elfin [read the full story…]