This review of antibiotic prophylactic treatments in relation to the risk of developing dry socket (DS) and site-specific infection (SSI) after lower third molar extraction included 16 RCTs. Antibiotic did reduce the risk of DS and SSI in health patients but the number needed to treat (NNT) was high so the use should be considered only after a careful assessment of an individual patient’s risk.
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This update of a Cochrane review of the relative benefits and harms of different surgical treatment modalities for oral cavity and oropharyngeal cancers includes 15 RCTs. Moderate-certainty evidence from 5 RCTs showed trials that elective neck dissection of clinically negative neck nodes at the time of removal of the primary oral cavity tumour is superior to therapeutic neck dissection, with increased survival and disease-free survival, and reduced locoregional recurrence.
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This review of the efficacy and safety of sialendoscopy in the treatment of obstructive diseases of the major salivary glands included 91 studies. The findings indicate and overall success rate of 80.9% (76.6 to 84.6 %) although all the included studies are observational, mainly retrospective and at medium to high risk of bias.
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This review of the effects of photobiomodulation (PBM) on pain, oedema, and trismus after extraction of impacted mandibular third molars included 33 RCTs. However 30 of the included studies were considered to be at high risk of bias, and while the results suggested small benefits for PBM in relation to reduction of pain and swelling these were not considered to be clinically important.
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Thte review of the percentage of impacted maxillary incisors that successfully erupt after surgical removal of supernumerary teeth included 15 studies. With the exception of one study all were retrospective with meta-analysis indicating a mean eruption success of 57.6% (95%CI; 47.8 to 67.0%). However the certainty of the evidence is very low to low.
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This review evaluating the efficacy of various radical and conservative surgical approaches in reducing recurrence rate for the treatment of solid/multicystic ameloblastoma included 7 retrospective cohort studies.The findings suggest that segmental resection was the best approach but the certainty of the evidence is low.
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This review of the effect of helmet use on the incidence of maxillofacial injuries due to cycling, e-bike, scooter, and e- scooter accidents included 14 studies. The findings suggest a significant reduction in the risk of maxillofacial injury with helmet use Odds ratio = 0.682 (95%CI; 0.565 to 0.822). Although all but 2 of the studies were retrospective and only 5 studies were considered to be of high quality .
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This review of the effect of different mouthwashes on gingival healing used after oral surgery in adults included 13 RCTs. The trials assessed 12 different products and concentrations and only one RCTs was considered to be at low risk of bias so the findings should be interpreted cautiously.
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This review estimating the nocebo response in dentistry from trials of analgesic treatment following third molar surgery included data from 50 RCTs. Adverse events (AEs) were roughly the same in placebo and active arms suggesting AEs may be attributed to the nocebo phenomenon.
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This review and network meta-analysis (NMA) of pharmacological treatments for the management of pain subsequent to simple and surgical tooth extraction included 85 RCTs. There was moderate- and high-certainty evidence that for surgical dental extractions that ibuprofen 200 to 400 mg plus acetaminophen 500 to 1,000 mg was the most effective for pain relief.
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