How much impact can optimism and positivity have on clinical outcomes in cardiovascular disease?

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Jake Crawshaw summarises a systematic review which investigates the relationships between positive psychological constructs and health outcomes in cardiovascular disease.

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CBT for school refusal

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Lucy Willetts publishes her debut blog on a Campbell systematic review, which focuses on psychosocial interventions for school refusal with primary and secondary school students.

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Quetiapine for schizophrenia: more transparency needed in clinical trial reporting

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Andrew Shepherd reports on a recent systematic review, meta-analysis and reappraisal of Quetiapine for schizophrenia, which concludes that Quetiapine IR has a small beneficial effect on psychotic symptoms, but also leads to weight gain and sedation.

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How does parenting impact on the emotional wellbeing of children?

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Sarah McDonald summarises a systematic review and meta-analysis of how parenting can impact on childhood anxiety, depression and internalising problems.

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CBTp and medication in the treatment of psychosis: summarising the best evidence

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Clive Adams presents a summary of the latest evidence for CBTp and medication in the treatment of psychosis. This blog was published alongside Clive’s talk at the Understanding Psychosis and Schizophrenia conference in Bath on 11 June 2015

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Pharmacotherapy for anxiety and comorbid alcohol use disorders

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Natasha Clarke summarises a recent Cochrane review of pharmacotherapy for anxiety and comorbid alcohol use disorders, which found only very low quality evidence about the effectiveness of medication (buspirone, paroxetine, sertraline) for treating patients with both conditions.

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Biological markers for treatment response in first episode psychosis

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Stephen Wood summarises a systematic review of biological markers for treatment response in first episode psychosis, which discusses a number of hot topics in this field including inflammation, infectious disease and oxidative stress.

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Sleep disruption during and after pregnancy may be associated with postpartum mental illness

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Susie Johnson summarises a systematic review that explores the relationship between sleep disruption and postpartum mental illness, which reports a link between self-reported poor sleep during and after pregnancy and the development of postpartum depression.

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Premature mortality in bipolar disorder

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Elena Marcus appraises a recent systematic review and meta-analysis of premature mortality in bipolar affective disorder, which finds that people with bipolar disorder have increased mortality rates compared with the general population.

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Does opioid antagonist medication improve the core features of autism spectrum conditions in children?

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Emma Langley looks at a systematic review of the effectiveness of the use of opioid antagonist medication in attenuating core symptoms of autism spectrum conditions in children

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