Group psychotherapies for schizophrenia

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Tracey Roberts appraises a systematic review of group psychotherapies for schizophrenia, which includes group CBT, music therapy, art therapy and social skills training.

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Lithium for schizophrenia: Cochrane find lack of evidence to support its use

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Raphael Underwood presents a new Cochrane review of lithium for schizophrenia, which assesses the use of lithium as a monotherapy and also in combination with antipsychotics.

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Microglial activity in psychosis and schizophrenia

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Samei Huda summarises a small PET brain imaging study, which looks at two cohorts (Ultra High Risk of Psychosis v Controls and Schizophrenia v Controls) to compare relative levels of microglial activity.

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Biological pathways, antipsychotics and schizophrenia

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Murtada Alsaif summarises a small cohort study that uses shotgun mass spectrometry proteomic profiling to unravel the molecular pathways involved with antipsychotic response in people with schizophrenia.

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Does QOF reduce hospitalisation for people with severe mental illness?

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Andres Fonseca appraises a regression analysis looking at the quality and outcomes framework (QOF) and the impact it has on psychiatric admissions in people with severe mental illness.

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Rise of the machine learning algorithm: the future of diagnosing schizophrenia?

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Samei Huda reviews a meta-analysis of multivariate pattern recognition studies, which aims to detect neuroimaging biomarkers for schizophrenia.

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Smoking and chronic mental illness: what’s the best way to quit or cut down?

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Meg Fluharty considers the findings of a BMJ State of the Art review, which looks at the evidence for smoking cessation in people with chronic mental illness such as schizophrenia, unipolar depression, bipolar depression, anxiety disorders and PTSD.

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Improving diagnosis of bipolar disorder: can blood-based diagnostic panels help?

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Can blood-based diagnostic panels help us reduce the misdiagnosis and inappropriate treatment often experienced by people with bipolar disorder? Murtada Alsaif reviews a recent retrospective study that has some encouraging findings for biologically identifying the disease.

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CBT for insomnia in people with active psychotic symptoms

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Sarah McDonald appraises the Better Sleep Trial (BEST), a pilot RCT which shows that CBT may be a promising treatment for insomnia in people with active psychotic symptoms.

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Integrated treatment for first episode psychosis: media hype versus reality

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Alex Langford reflects on the media hype surrounding a new RCT of the NAVIGATE intervention; a comprehensive, multidisciplinary, team-based treatment approach for first episode psychosis.

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