Specialist depression service may help people with persistent depression


Ben Hannigan reports on a recent RCT of the efficacy and cost-effectiveness of a specialist depression service versus usual specialist mental health care to manage persistent depression.

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Psychosocial interventions for cannabis use disorder #CannabisMatters


Ian Hamilton presents the findings of a recent Cochrane review, which finds that despite the large number of cannabis users seeking treatment, we still know relatively little about the best psychosocial interventions for cannabis use disorder.

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Long-acting injectable paliperidone palmitate for schizophrenia


Tracey Roberts summarises a recent RCT of the efficacy and safety of paliperidone palmitate 3-month formulation for patients with schizophrenia.

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Mindfulness-based cognitive therapy can prevent recurrent depression


Sarah McDonald reports on a meta-analysis published yesterday, which found that when compared with active treatment, mindfulness-based cognitive therapy resulted in a reduced risk of depressive relapse.

This blog also features a podcast interview with the lead author of the research, Professor Willem Kuyken.

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Mindfulness-based cognitive therapy cannot substitute maintenance antidepressants for preventing depression relapse


Ioana Cristea takes a closer look at a recent non-inferiority RCT, which compares mindfulness-based cognitive therapy (MBCT) plus discontinued antidepressants versus MBCT and maintenance antidepressants.

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Is the NICE guideline for bipolar disorder biased in favour of psychosocial interventions?


Guy Goodwin reviews a new paper in the Lancet Psychiatry by Jauhar, McKenna and Laws, that calls into question the trustworthiness of the NICE bipolar disorder guidance.

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Can psychotherapy reduce the risk of relapse or recurrence of depression?


Sarah McDonald appraises a new systematic review that asks if psychological interventions can prevent relapse in adults who have recovered from depression.

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Psychotherapy can reduce the risk of relapse or recurrence of depression


Raluca Lucacel summarises a meta-analysis of psychological interventions in preventing recurrence of depression, which includes trials on cognitive behavioural therapy, interpersonal therapy and mindfulness-based cognitive therapy.

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Mindfulness-based cognitive therapy to prevent depression

In April 2015 we blogged PREVENT and concluded that mindfulness based cognitive therapy is a promising intervention for preventing depression.

André Tomlin presents the results of the PREVENT RCT published today in The Lancet, which investigates the effectiveness and cost-effectiveness of mindfulness-based cognitive therapy compared with maintenance antidepressant treatment in the prevention of depressive relapse or recurrence.

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Eating disorders: mapping the (lack of) evidence


Helen Bould summarises a recent review that maps the evidence for the prevention and treatment of eating disorders in young people. Her conclusion? A call to arms for more better quality research to help people affected by these serious illnesses.

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