Cognitive stimulation therapy for dementia

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Clarissa Giebel summarises a multicentre RCT that assesses the clinical effectiveness and cost-effectiveness of individual cognitive stimulation therapy for dementia.

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Aripiprazole for treatment-resistant depression in older adults

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Sarsha Wilson publishes her debut blog about a recent RCT on the efficacy, safety and tolerability of augmentation pharmacotherapy with aripiprazole for treatment-resistant depression in later life.

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A new MANTRA for treating anorexia nervosa? The MOSAIC study

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Helen Bould considers the findings of the MOSAIC RCT that compares the Maudsley Model of Anorexia Nervosa Treatment for Adults (MANTRA) with Specialist Supportive Clinical Management (SSCM) in outpatients with broadly defined Anorexia Nervosa.

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Empowering patients can lead to fewer hospital readmissions, according to small RCT

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Clarissa Giebel presents the findings of a small RCT that evaluates the impact of a social work care coordination intervention on hospital readmissions in older adults.

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Lamotrigine, quetiapine and folic acid for bipolar depression: the CEQUEL trial

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Michael Ostacher considers the findings of the CEQUEL trial, which asks: Does lamotrigine treat bipolar depression when added to quetiapine, and does adding folic acid help any more?

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Donepezil, nursing home placement and Alzheimer’s Disease

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Caroline Struthers reports on the findings of a follow-up paper of the DOMINO-AD trial, which compares Donepezil and Memantine for Moderate to Severe Alzheimer’s Disease, and looks at the effects these two drugs have on nursing home placement.

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CBT plus mother-child interaction for anxiety disorder

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Paul Ramchandani considers an RCT of treatment for childhood anxiety disorder in the context of maternal anxiety disorder, which finds that mother-child interaction might be of value for childhood anxiety disorder.

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Pivotal response treatment is promising for children with autism

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Rosalyn Nelson presents the findings of a small RCT of Pivotal Response Treatment groups for parents of children with autism, which has promising results in terms of encouraging children to communicate.

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Community treatment orders still don’t work at 36 months: OCTET trial follow up

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Raphael Underwood presents the 3 year follow up of the OCTET trial of community treatment orders for people with psychosis, which finds no significant difference on readmission or disengagement for patients on CTOs compared to those discharged to voluntary status via Section 17 leave.

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