Adding antidepressants to antipsychotics in schizophrenia: do they work, for what, and are they safe?

7687091514_3bffb55cb0_k

Alex Langford explores the emerging findings from a recent meta-analysis looking at the efficacy and safety of antidepressants added to antipsychotics for people with schizophrenia and schizophrenia-like psychosis.

[read the full story...]

Have the EAGLES landed? Safety of varenicline, bupropion and NRT in smokers with and without mental illnesses

photo-1457383457550-47a5cfdbab17

Paul Christiansen presents the results of the EAGLES RCT into the neuropsychiatric safety and efficacy of varenicline, bupropion, and nicotine patches in smokers with and without psychiatric disorders.

[read the full story...]

Outcomes in first episode manic psychosis

photo-1423420634464-89006b3454a8

Matthew Broome writes his debut Mental Elf blog on a three-year clinical and functional outcome comparison between first episode manic psychosis and first-episode schizophrenia.

[read the full story...]

Schizophrenia and urban deprivation: When the facts change, I change my mind. What do you do?

photo-1430760814266-9c81759e5e55

Samei Huda reviews a recent study of schizophrenia and subsequent urban deprivation, which revisits the social drift hypothesis.

[read the full story...]

Antipsychotic overprescribing in people with learning disabilities #UCLJournalClub

15910692553_1e904570cb_h

Tayla McCloud from the #UCLJournalClub presents the findings of a cohort study showing that antipsychotics are being over-prescribed in people with learning disabilities.

[read the full story...]

Childhood maltreatment and bipolar disorder

7166752339_902ff47895_k

Emily Currell writes her debut Mental Elf blog about a recent Lancet Psychiatry systematic review, which reports that childhood maltreatment is associated with an unfavourable course of bipolar disorder in adult years.

[read the full story...]

Mental health crisis care: clinical and cost effectiveness of models of care

Punctuation marks made of puzzle pieces

Caroline Leah publishes her debut blog on crisis care for people with mental health issues, which concludes that better quality evidence is needed to support the overall effectiveness of crisis care interventions.

[read the full story...]

Psychotropic medication in pregnancy: new evidence may help achieve a safe balance

pregnant with ipad

Joanne Wallace considers a recent health technology assessment on the risks and benefits of psychotropic medication in pregnancy, which supports previous associations between valproate and adverse child outcomes.

[read the full story...]

Prognosis of brief psychotic episodes

3917186281_bb24ceabb8_o

Samei Huda presents the findings of a new meta-analysis, which explores the prognostic significance of competing ways of defining and measuring brief psychotic episodes.

[read the full story...]