Do different groups of people with schizophrenia respond differently to different antipsychotics?

roberto-sorin-RS0-h_pyByk-unsplash

Murtada Alsaif considers a systematic review and meta-analysis published in the Lancet Psychiatry exploring the response of different subgroups of patients with schizophrenia to different antipsychotic drugs.

[read the full story...]

Antidepressant withdrawal or depression relapse? International guidelines on antidepressant discontinuation are unclear

roberto-sorin-RS0-h_pyByk-unsplash

Adele Framer summarises a systematic review which finds that major guidelines on antidepressant discontinuation only give clinicians vague guidance on distinguishing withdrawal from relapse.

[read the full story...]

Risperidone and aripiprazole: genotype, metabolism and dosage

CYP2D6 genotyping before starting treatment might be valuable in clinical practice for individualising risperidone and aripiprazole treatment.

Dolly Sud writes her debut elf blog on a recent retrospective analysis, which compares dose changes of risperidone and aripiprazole with patients’ individual genotype.

[read the full story...]

Focus of pharmacotherapy for people with learning disabilities and mental ill health should be on specific forms of psychopathology

Aim

A number of studies have suggested that prevalence rates of mental ill-health in people with learning disabilities is higher than in the general population, although issues of definition have made it difficult to make clear comparisons. The authors of this review set out to identify trends and developments in the study of psychopathology in people [read the full story…]