This review of the effect of additives incorporated into lidocaine solution on the success of inferior alveolar nerve block (IANB) included 12 RCTs. The findings suggest that additives did not improve the success rate of IANB but the evidence is of low to very low certainty.
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Modern local anaesthetics have transformed the practice of dentistry. However a proportion of injections fail to achieve pulpal anaesthesia. This trial set out to find if the addition of mannitol to lidocaine with epinephrine improved its efficacy. Forty patients were randomised to receive an inferior alveolar nerve (IAN) block in 3 separate appointments spaced at [read the full story…]
