Proton-pump inhibitors and risk of dementia

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Caroline Struthers reports on a recent prospective cohort study which finds a strong association between the use of proton pump inhibitors and a significantly increased risk of dementia.

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Impact of functional alterations on quality of life in Alzheimer disease

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Clarissa Giebel analyses a qualitative study of how functional alterations impact quality of life in Alzheimer disease.

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Statins for dementia prevention: well-tolerated, but Cochrane highlight lack of evidence

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Rosalyn Nelson summarises a recently updated Cochrane systematic review of statins for dementia prevention, which finds no evidence to support their use.

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Cognitive stimulation therapy for dementia

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Clarissa Giebel summarises a multicentre RCT that assesses the clinical effectiveness and cost-effectiveness of individual cognitive stimulation therapy for dementia.

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Cognitive tests for dementia: MMSE, Mini-Cog and ACE-R

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Akshay Nair explores the results of a systematic review of cognitive tests for dementia and mild cognitive impairment, which focuses on the MMSE, Mini-Cog, ACE-R and MoCA instruments. Along the way he explains how diagnostic tests work and how sensitivity and specificity are useful measures to get your head around.

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Donepezil, nursing home placement and Alzheimer’s Disease

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Caroline Struthers reports on the findings of a follow-up paper of the DOMINO-AD trial, which compares Donepezil and Memantine for Moderate to Severe Alzheimer’s Disease, and looks at the effects these two drugs have on nursing home placement.

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Do house calls benefit older adults with dementia?

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Clarissa Giebel looks at a US study on the impact of ‘house calls’ on health and social service use by people with dementia, and asks some critical questions of the research.

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Can higher educational attainment help lower dementia risk?

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Raluca Lucacel summarises a recent meta-analysis of prospective cohort studies, which investigates the dose-response between education and the risk of dementia.

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