Pain during orthodontic treatment: non-pharmacological interventions

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14 trials were included in this Cochrane review of non-pharmacological interventions for orthodontic pain. The findings were inconclusive although there is some evidence that low-level laser therapy may help.

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One size does not fit all: divergent outcomes from CBT and antidepressants for depression

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Suzanne Dash explores a recent meta-analysis of CBT and antidepressants for depression, which looked at negative and positive responses to treatment and what predicted different outcomes.

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iCBT for depression: how does it work?

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Mark Smith presents the findings from a qualitative systematic review of iCBT for depression, which tries to unearth the mechanisms of change of internet-based or computerised cognitive behavioural therapy.

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Rapid response to eating disorders predicts better outcomes

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Francesca Solmi writes her debut elf blog on a recent systematic review and meta-analysis of rapid response to eating disorders, which finds that early treatment of anorexia, bulimia and binge eating disorder is associated with moderate improvements in behavioural and cognitive outcomes.

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CBT for Autism Spectrum Disorders and comorbid mental illness

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Alix Dixon presents a recent systematic review on the effectiveness of CBT for autism spectrum disorders and comorbid anxiety or depression.

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iCBT may be an effective treatment for PTSD

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André Tomlin explores a recent systematic review and meta-analysis of the effectiveness of Internet-delivered cognitive behavioural therapy (iCBT) for post-traumatic stress disorder (PTSD).

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Specialist depression service may help people with persistent depression

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Ben Hannigan reports on a recent RCT of the efficacy and cost-effectiveness of a specialist depression service versus usual specialist mental health care to manage persistent depression.

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Training alone doesn’t improve outcomes for depression in primary care

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Linda Gask writes her debut Mental Elf blog on a recent systematic review, which evaluates healthcare team training programs that aim to improve depression in primary care.

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Antidepressants and psychotherapy for OCD in adults: network meta-analysis

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Alan Underwood summarises a recent network meta-analysis of medication and talking treatments for OCD (obsessive-compulsive disorder) in adults.

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Behavioural activation not inferior to CBT for depression: the COBRA RCT

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Ioana Cristea appraises the recently published COBRA randomised controlled trial, which concludes that behavioural activation is non-inferior to cognitive behavioural therapy for depression, and may offer significant cost savings.

This blog also features a podcast interview with the lead author: Professor David Richards from Exeter University.

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