Do analgesics before dental treatment reduce post treatment pain in children?

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This Cochrane review found 5 RCTs of pre-op analgesics prior to dental treatment for children under local anaesthetic. The evidence as insufficient to determine a benefit but there may be a benefit prior to orthodontic band placement. Further high quality studies are needed.

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Third molar removal: antibiotics reduced risk of dry socket

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This review of antibiotic prophylaxis for the removal of third molars included 22 RCTs and suggest that antibiotic use lowered the infection risk by 60%. The number pf patients needed to treat to prevent one infection was 14 (95%CI;11-19).

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Oral leukoplakia: very limited evidence for treatments

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The aim of this Cochrane review was to assess the effectiveness, safety and acceptability of treatments for oral leukoplakia in preventing oral cancer.

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Fluoride mouthrinse: regular supervised use reduces tooth decay in children

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This Cochrane review includes 37 RCTs and found regular supervised use of fluoride mouthrinse by children and adolescents is associated with a large reduction in caries increment in permanent teeth.

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Dental implants: survival rates of turned and anodised-surface dental implants

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38 studies were included in this review comparing survival rates of turned and anodised-surface dental implants. The findings suggest that turned implants have a higher failure rate but the evidence is limited as the review includes a substantial proportion of retrospective studies.

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Institutional smoking bans reduce secondhand smoke exposure and harms, but more research is needed

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Olivia Maynard summarises a recent Cochrane systematic review about the impact of institutional smoking bans on reducing harms and secondhand smoke exposure in hospitals, universities and prisons.

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Prolonged bleeding after tooth extraction – no evidence on treatment from trials

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This Cochrane review did not identify any randomised controlled trials that evaluated the effects of different interventions for the treatment of post-extraction bleeding. Clinicians must use their clinical experience to determine the most appropriate means of treating this condition, depending on patient-related factors.

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Cochrane find no evidence for as required PRN medication for mental health inpatients

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John Baker summarises an updated Cochrane review on ‘as required’ PRN medication regimens for seriously mentally ill people in hospital, which finds no randomised controlled trials that support this widely used intervention.

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Psychosocial interventions for cannabis use disorder #CannabisMatters

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Ian Hamilton presents the findings of a recent Cochrane review, which finds that despite the large number of cannabis users seeking treatment, we still know relatively little about the best psychosocial interventions for cannabis use disorder.

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Treatment for depression in traumatic brain injury: Cochrane find no evidence for non-pharmacological interventions

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Eleanor Kennedy summarises a recent Cochrane systematic review, which finds no evidence to support the use of non-pharmacological interventions for depression in traumatic brain injury.

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