Mental illness, challenging behaviour and psychotropic drugs #UCLJournalClub

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Join us at 2-3pm on Wednesday 18th May for the #UCLJournalClub, which will be live broadcasted on YouTube and live tweeted by the @LearningDisElf

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Self-harm in primary care: more prescribing than referrals

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Olivia Kirtley and Alys Cole-King present a major new cohort study, which includes worrying evidence about the clinical management of patients in primary care following self-harm.

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Collaborative care for depression: acceptable, effective and affordable

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Ben Hannigan writes his debut blog on the CADET cluster RCT, which investigates the clinical effectiveness and cost-effectiveness of collaborative care for depression in UK primary care.

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Mindfulness-based cognitive therapy cannot substitute maintenance antidepressants for preventing depression relapse

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Ioana Cristea takes a closer look at a recent non-inferiority RCT, which compares mindfulness-based cognitive therapy (MBCT) plus discontinued antidepressants versus MBCT and maintenance antidepressants.

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Does the placebo effect inflate the effectiveness of psychotherapy?

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Sarah Knowles reviews a recent meta-analysis about the effects of blinding on the outcomes of psychotherapy and pharmacotherapy for adult depression.

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Commonly prescribed psychiatric drugs: do they work?

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John Baker summarises a review of commonly prescribed medication that covers seven psychiatric drugs, including antidepressants, antipsychotics, benzodiazepines, amphetamines, methylphenidate and cholinesterase inhibitors.

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Antidepressants: benefits and harms in children and adults

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Samei Huda discusses the findings of a recent review into suicidality and aggression during antidepressant treatment. The systematic review and meta-analyses were based on clinical study reports and included some important adverse effects of antidepressants in children and young people.

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Can a machine learning approach help us predict what specific treatments work best for individuals with depression?

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Marcus Munafo explores a recent study that uses a machine learning approach across two trials (STARD*D and CO-MED) to try and predict treatment outcomes (primarily focusing on the antidepressant citalopram) for depression.

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CBT plus medication for treatment-resistant depression: the CoBalT RCT long-term follow-up

In February 2016 we blogged CoBalT and concluded that CBT plus usual care (including antidepressants) is clinically and cost effective in the long-term for people whose depression has not responded to medication.

Sarah McDonald considers the findings of the CoBalT RCT long-term follow-up, which finds that CBT plus antidepressants are clinically and cost effective for treatment-resistant depression in primary care.

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Top mental health blogs in 2015

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André Tomlin presents his review of 2015, the year when the Mental Elf came of age. He highlights our top mental health blogs, showcases the #WeCATS and #ElfCampfire activities and explains how the new National Elf Service website can help you engage more with relevant and reliable research.

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