What impact are psychotropic drugs having on our physical health?


John Baker summarises the findings of a recent review of people with schizophrenia, bipolar disorder and depression. The study looks at the adverse effects on physical health of psychotropic drugs (antipsychotics, antidepressants and mood stabilisers).

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No link between SSRI use and violent crime in over 25s


Sarah McDonald considers the implications of a recent cohort study of SSRI use and violent crime, which suffered from the usual headline grabbing media coverage, so typical of research about young people, violence, crime, drugs and mental health.

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Antidepressants for depression: new BAP guidance


Helge Hasselmann summarises the recently published evidence-based guidance on antidepressants for depression published by the British Association for Psychopharmacology.

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Combined methylphenidate and citalopram may help older people with depression recover faster

Depressed older man

Lisa Burscheidt summarises a recent randomised controlled trial of combined methylphenidate and citalopram for depression in older people, which presents promising but limited findings.

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Antidepressants for depression in cancer: Cochrane review highlights lack of evidence

Female cancer patient

Kirsten Lawson reports on a recent Cochrane systematic review, which highlights a lack of high quality trials about the efficacy and safety of antidepressants for depression in cancer.

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Medication for self-harm: new Cochrane review finds very limited evidence to support its use


Dochka Hristova reports on a new Cochrane review of pharmacological interventions for self-harm in adults, which looks at the treatment effect on repetition of self-harm of antidepressants, antipsychotics, mood stabilisers and dietary supplements.

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Treatments for delusional disorder


Andrew Shepherd summarises a Cochrane systematic review of treatments for delusional disorder, which finds only 1 small RCT looking at treating the condition with medication or psychotherapy compared to placebo.

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Antidepressants during pregnancy and risk of persistent pulmonary hypertension of the newborn


Meg Fluharty examines the findings of a recent study, which looks at the risk of persistent pulmonary hypertension of the newborn (PPHN) when mothers take antidepressants during pregnancy.

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Pharmacotherapy for anxiety and comorbid alcohol use disorders


Natasha Clarke summarises a recent Cochrane review of pharmacotherapy for anxiety and comorbid alcohol use disorders, which found only very low quality evidence about the effectiveness of medication (buspirone, paroxetine, sertraline) for treating patients with both conditions.

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Dose equivalents of antidepressants: standardising prescribing between different drugs


Andrew Shepherd summarises a meta-analysis, which looks at the dose equivalents of antidepressants by bringing together data from 83 trials of 23 different antidepressants.

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