Results: 434

For: meta-analysis

Is the NICE guideline for bipolar disorder biased in favour of psychosocial interventions?

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Guy Goodwin reviews a new paper in the Lancet Psychiatry by Jauhar, McKenna and Laws, that calls into question the trustworthiness of the NICE bipolar disorder guidance.

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Orthodontic retention – little high quality evidence to recommend any one approach to over another

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15 studies involving 1722 patients were included in this Cochrane review update on orthodontic retention. However, there was insufficient high quality evidence to make recommendations on retention procedures.

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Cognitive tests for dementia: MMSE, Mini-Cog and ACE-R

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Akshay Nair explores the results of a systematic review of cognitive tests for dementia and mild cognitive impairment, which focuses on the MMSE, Mini-Cog, ACE-R and MoCA instruments. Along the way he explains how diagnostic tests work and how sensitivity and specificity are useful measures to get your head around.

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Platform-switching dental implants improved bone preservation in short term

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This review of platform-switching of dental implants included 17 RCTs and found that bone loss was lower than in regular platform implants, mean difference = -0.41mm (95%CI; -0.58 to -0.24) with no difference in failure rates RR = 1.10 (95%CI; 0.6–2.02).

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Group psychotherapies for schizophrenia

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Tracey Roberts appraises a systematic review of group psychotherapies for schizophrenia, which includes group CBT, music therapy, art therapy and social skills training.

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Coronal pulpotomy in permanent molars

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This review of coronal pulpotomy in permanent teeth demonstrated good survival at 2 years 92% (95%CI; 84 -100). However as the majority of studies were observational they should be viewed cautiously until further high quality RCTs are available.

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Sealants or fluoride varnish for caries prevention?

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This Cochrane review update included 8 trials involving 1746 participants. Some low-quality evidence suggesting the superiority of resin-based fissure sealants over fluoride varnish applications was identified

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No sexual health history please, we’re British!

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Kirsten Lawson presents the results of a systematic review of observational cross-sectional studies, which looks at the worldwide prevalence of HIV, hepatitis B and hepatitis C in people with severe mental illness.

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Lithium for schizophrenia: Cochrane find lack of evidence to support its use

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Raphael Underwood presents a new Cochrane review of lithium for schizophrenia, which assesses the use of lithium as a monotherapy and also in combination with antipsychotics.

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