Articaine better than lignocaine for routine molar anaesthesia


This systematic review was originally published in the Journal of Dentistry in 2010.

The Centre for Reviews and Dissemination have now appraised the quality of the review and written a structured abstract of it.

They conclude that the review conducted a comprehensive search strategy, with a risk of some publication bias due to their inclusion of English language papers only.  The reviewers did not carry out blind, independent assessments of the quality of the individual papers.

That said, it seems unlikely that any bias was so significant as to change the direction of the findings.

The review found that articaine was more effective than lignocaine in providing anaesthetic success in the first molar region for routine dental procedures. Note that subsequent pain scores were all significantly higher.

The two drugs were similar in terms of adverse events.

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Douglas Badenoch

I am an information scientist with an interest in making knowledge from systematic research more accessible to people who need it. This means you. I've been attempting this in the area of Evidence-Based Health Care since 1995. So far the results have been mixed. For some reason we expected busy clinicians to search databases and appraise papers instead of seeing patients. We also expected publishers to make the research freely available to the people who paid for it.. Ha! Hence The National Elf service.

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